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Vizgen MERSCOPE

Mouse brain

GSM8464548

silver Interactive viewer Alzheimer disease ✓ Verified publication
Mouse brain preview
print(sdata)
SpatialData object
├── Shapes
│     └── 'cells': GeoDataFrame shape: (113880, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (113880, 395)
with coordinate systems:
    ▸ 'global', with elements:
        cells (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("wxkXLjpenOnbeQum0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("wxkXLjpenOnbeQum")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download wxkXLjpenOnbeQum0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/wxkXLjpenOnbeQum

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid wxkXLjpenOnbeQum

License: NCBI GEO policy

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Part of collection
geo-gse275026→
8 datasets · publication

Metadata

Technology
Vizgen MERSCOPE
Organism
mouse
Tissue
brain
Condition
Alzheimer disease
Modality
RNA
Observations (cells)
113,880
Tier
silver
Size
35.0 MB
Sample ID
GSM8464548
License
NCBI GEO policy
Published
Aug 7, 2025

Cite this dataset

doi.org/10.1038/s41586-025-09662-z ↗
BibTeX
@article{geo:GSE275026,
  doi = {10.1038/s41586-025-09662-z},
  title = {GSM8970742},
  year = {2025}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB