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Visium

Mouse lung

GSM7978619

bronze Interactive viewer H&E pulmonary fibrosis Provisional
Mouse lung preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM7978619_B1_hires_image': DataArray[cyx] (3, 2000, 1817)
│     └── 'GSM7978619_B1_lowres_image': DataArray[cyx] (3, 600, 545)
├── Shapes
│     └── 'GSM7978619_B1': GeoDataFrame shape: (2775, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2775, 32285)
with coordinate systems:
    ▸ 'GSM7978619_B1', with elements:
        GSM7978619_B1_hires_image (Images), GSM7978619_B1_lowres_image (Images), GSM7978619_B1 (Shapes)
    ▸ 'GSM7978619_B1_downscaled_hires', with elements:
        GSM7978619_B1_hires_image (Images), GSM7978619_B1 (Shapes)
    ▸ 'GSM7978619_B1_downscaled_lowres', with elements:
        GSM7978619_B1_lowres_image (Images), GSM7978619_B1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("3JTVLlyZPSZ436Qr0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("3JTVLlyZPSZ436Qr")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 3JTVLlyZPSZ436Qr0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/3JTVLlyZPSZ436Qr

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 3JTVLlyZPSZ436Qr

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
mouse
Tissue
lung
Condition
pulmonary fibrosis
Modality
RNA
Observations (spots)
2,775
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,817 × 2,000 px
mpp
4.049 µm/px
Size
12.5 MB
Sample ID
GSM7978619
License
NCBI GEO policy
Published
Jan 7, 2025

Cite this dataset

doi.org/10.1038/s41586-025-08727-3 ↗
BibTeX
@article{Guo_2025,
  title = {Histological signatures map anti-fibrotic factors in mouse and human lungs},
  volume = {641},
  ISSN = {1476-4687},
  url = {http://dx.doi.org/10.1038/s41586-025-08727-3},
  DOI = {10.1038/s41586-025-08727-3},
  number = {8064},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  author = {Guo, Jason L. and Griffin, Michelle and Yoon, Jung-Ki and Lopez, David M. and Zhu, Yili and Lu, John M. and Mikos, Georgios and Parker, Jennifer B. L. and Mascharak, Shamik and Brenac, Camille and Guardino, Nicholas J. and Abbas, Darren B. and Li, Dayan J. and Valencia, Caleb and Liang, Norah E. and Januszyk, Michael and Chang, Howard Y. and Wan, Derrick C. and Desai, Tushar J. and Longaker, Michael T.},
  year = {2025},
  month = Mar,
  pages = {993–1004}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB