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Visium

Human liver

GSM8657781

silver Interactive viewer H&E hepatoblastoma ✓ Verified publication
Human liver preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8657781_H1180_full_image': DataTree[cyx] (3, 3000, 3000), (3, 1500, 1500), (3, 750, 750), (3, 375, 375), (3, 187, 187)
│     ├── 'GSM8657781_H1180_hires_image': DataArray[cyx] (3, 2000, 2000)
│     └── 'GSM8657781_H1180_lowres_image': DataArray[cyx] (3, 600, 600)
├── Shapes
│     └── 'GSM8657781_H1180': GeoDataFrame shape: (4192, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4192, 18085)
with coordinate systems:
    ▸ 'GSM8657781_H1180', with elements:
        GSM8657781_H1180_full_image (Images), GSM8657781_H1180_hires_image (Images), GSM8657781_H1180_lowres_image (Images), GSM8657781_H1180 (Shapes)
    ▸ 'GSM8657781_H1180_downscaled_hires', with elements:
        GSM8657781_H1180_hires_image (Images), GSM8657781_H1180 (Shapes)
    ▸ 'GSM8657781_H1180_downscaled_lowres', with elements:
        GSM8657781_H1180_lowres_image (Images), GSM8657781_H1180 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("iouW5pmJXlILygwh0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("iouW5pmJXlILygwh")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download iouW5pmJXlILygwh0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/iouW5pmJXlILygwh

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid iouW5pmJXlILygwh

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
liver
Condition
hepatoblastoma
Modality
RNA
Observations (spots)
4,192
Tier
silver
Chemistry
Visium CytAssist v2
Resolution
3,000 × 3,000 px
mpp
3.696 µm/px
Size
92.8 MB
Sample ID
GSM8657781
License
NCBI GEO policy
Published
Feb 7, 2025

Cite this dataset

doi.org/10.1016/j.jhep.2025.01.031 ↗
BibTeX
@article{M_nter_2025,
  title = {Multiomic analysis uncovers a continuous spectrum of differentiation and Wnt-MDK-driven immune evasion in hepatoblastoma},
  volume = {83},
  ISSN = {0168-8278},
  url = {http://dx.doi.org/10.1016/j.jhep.2025.01.031},
  DOI = {10.1016/j.jhep.2025.01.031},
  number = {2},
  journal = {Journal of Hepatology},
  publisher = {Elsevier BV},
  author = {Münter, Daniel and de Faria, Flavia W. and Richter, Mathis and Aranda-Pardos, Irene and Hotfilder, Marc and Walter, Carolin and Paga, Enya and Inserte, Clara and Albert, Thomas K. and Roy, Rajanya and Rahman, Shariyah and Riedel, Nicole C. and Müller, Volker and Pascher, Andreas and Wiebe, Karsten and Schmid, Irene and Vokuhl, Christian and Winkler, Beate and Jüttner, Eva and Vieth, Simon and Mücke, Urs and Kluiver, Thomas A. and Peng, Weng Chuan and Rossig, Claudia and Schlué, Jerome and Madadi-Sanjani, Omid and Sandmann, Sarah and Hartmann, Wolfgang and A-Gonzalez, Noelia and Soehnlein, Oliver and Kerl, Kornelius},
  year = {2025},
  month = Aug,
  pages = {367–382}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB