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Human liver

NCBI833

silver Interactive viewer H&E acute liver failure ✓ Verified publication
Human liver preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI833_full_image': DataTree[cyx] (3, 9432, 9312), (3, 4716, 4656), (3, 2358, 2328), (3, 1179, 1164)
├── Shapes
│     └── 'NCBI833_spots': GeoDataFrame shape: (4992, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4992, 33538)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI833_full_image (Images), NCBI833_spots (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("7taUrn6nWTQ9esQ10000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("7taUrn6nWTQ9esQ1")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 7taUrn6nWTQ9esQ10000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/7taUrn6nWTQ9esQ1

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 7taUrn6nWTQ9esQ1

License: CC BY-NC-SA 4.0 (noncommercial)

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
Multimodal decoding of human liver regeneration [st_mouse]→
19 datasets · comparison

Metadata

Technology
Visium
Organism
human
Tissue
liver
Condition
acute liver failure
Modality
RNA
Observations (spots)
4,992
Tier
silver
Chemistry
Visium v1
Resolution
9,312 × 9,432 px
mpp
0.881 µm/px
Size
200 MB
Sample ID
NCBI833
License
CC BY-NC-SA 4.0 NonCommercial
Published
Feb 1, 2023

Cite this dataset

doi.org/10.1038/s41586-024-07376-2 ↗
BibTeX
@article{Matchett_2024,
  title = {Multimodal decoding of human liver regeneration},
  volume = {630},
  ISSN = {1476-4687},
  url = {http://dx.doi.org/10.1038/s41586-024-07376-2},
  DOI = {10.1038/s41586-024-07376-2},
  number = {8015},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  author = {Matchett, K. P. and Wilson-Kanamori, J. R. and Portman, J. R. and Kapourani, C. A. and Fercoq, F. and May, S. and Zajdel, E. and Beltran, M. and Sutherland, E. F. and Mackey, J. B. G. and Brice, M. and Wilson, G. C. and Wallace, S. J. and Kitto, L. and Younger, N. T. and Dobie, R. and Mole, D. J. and Oniscu, G. C. and Wigmore, S. J. and Ramachandran, P. and Vallejos, C. A. and Carragher, N. O. and Saeidinejad, M. M. and Quaglia, A. and Jalan, R. and Simpson, K. J. and Kendall, T. J. and Rule, J. A. and Lee, W. M. and Hoare, M. and Weston, C. J. and Marioni, J. C. and Teichmann, S. A. and Bird, T. G. and Carlin, L. M. and Henderson, N. C.},
  year = {2024},
  month = May,
  pages = {158–165}
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB