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Visium

Human coronary artery

GSM8658912

silver Interactive viewer H&E atherosclerosis ✓ Verified publication
Human coronary artery preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8658912_sample2d1_full_image': DataTree[cyx] (3, 3000, 3000), (3, 1500, 1500), (3, 750, 750), (3, 375, 375), (3, 187, 187)
│     ├── 'GSM8658912_sample2d1_hires_image': DataArray[cyx] (3, 1769, 2000)
│     └── 'GSM8658912_sample2d1_lowres_image': DataArray[cyx] (3, 531, 600)
├── Shapes
│     └── 'GSM8658912_sample2d1': GeoDataFrame shape: (732, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (732, 18085)
with coordinate systems:
    ▸ 'GSM8658912_sample2d1', with elements:
        GSM8658912_sample2d1_full_image (Images), GSM8658912_sample2d1_hires_image (Images), GSM8658912_sample2d1_lowres_image (Images), GSM8658912_sample2d1 (Shapes)
    ▸ 'GSM8658912_sample2d1_downscaled_hires', with elements:
        GSM8658912_sample2d1_hires_image (Images), GSM8658912_sample2d1 (Shapes)
    ▸ 'GSM8658912_sample2d1_downscaled_lowres', with elements:
        GSM8658912_sample2d1_lowres_image (Images), GSM8658912_sample2d1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("hKanchbuuGE2cZ7G0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("hKanchbuuGE2cZ7G")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download hKanchbuuGE2cZ7G0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/hKanchbuuGE2cZ7G

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid hKanchbuuGE2cZ7G

License: CC BY 4.0

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Metadata

Technology
Visium
Organism
human
Tissue
coronary artery
Condition
atherosclerosis
Modality
RNA
Observations (spots)
732
Tier
silver
Chemistry
Visium CytAssist v2
Resolution
2,000 × 1,769 px
mpp
2.129 µm/px
Size
22.4 MB
Sample ID
GSM8658912
License
CC BY 4.0
Published
Feb 11, 2025

Cite this dataset

doi.org/10.3390/ijms26051949 ↗
BibTeX
@article{Li_2025,
  title = {Spatial Gene Expression of Human Coronary Arteries Revealed the Molecular Features of Diffuse Intimal Thickening in Explanted Hearts},
  volume = {26},
  ISSN = {1422-0067},
  url = {http://dx.doi.org/10.3390/ijms26051949},
  DOI = {10.3390/ijms26051949},
  number = {5},
  journal = {International Journal of Molecular Sciences},
  publisher = {MDPI AG},
  author = {Li, Boaz and Leung, Samuel and Elishaev, Maria and Cheng, Wan Hei and Mocci, Giuseppe and Björkegren, Johan L. M. and Lai, Chi and Singh, Amrit and Wang, Ying},
  year = {2025},
  month = Feb,
  pages = {1949}
}

Source: NCBI GEO ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB