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Visium

Human aortic valve leaflet

GSM9759911

bronze Interactive viewer aortic valve stenosis Provisional
Human aortic valve leaflet preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9759911_Patient_23V_hires_image': DataArray[cyx] (3, 1960, 2000)
│     └── 'GSM9759911_Patient_23V_lowres_image': DataArray[cyx] (3, 588, 600)
├── Shapes
│     └── 'GSM9759911_Patient_23V': GeoDataFrame shape: (1512, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1512, 36601)
with coordinate systems:
    ▸ 'GSM9759911_Patient_23V', with elements:
        GSM9759911_Patient_23V_hires_image (Images), GSM9759911_Patient_23V_lowres_image (Images), GSM9759911_Patient_23V (Shapes)
    ▸ 'GSM9759911_Patient_23V_downscaled_hires', with elements:
        GSM9759911_Patient_23V_hires_image (Images), GSM9759911_Patient_23V (Shapes)
    ▸ 'GSM9759911_Patient_23V_downscaled_lowres', with elements:
        GSM9759911_Patient_23V_lowres_image (Images), GSM9759911_Patient_23V (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("MdqBOmk6RwenFiyy0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("MdqBOmk6RwenFiyy")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download MdqBOmk6RwenFiyy0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/MdqBOmk6RwenFiyy

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid MdqBOmk6RwenFiyy

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
aortic valve leaflet
Condition
aortic valve stenosis
Modality
RNA
Observations (spots)
1,512
Tier
bronze
Chemistry
Visium v1
Size
6.6 MB
Sample ID
GSM9759911
License
NCBI GEO policy
Published
Jun 3, 2026

Cite this dataset

doi.org/10.1161/atvbaha.126.324694 ↗
BibTeX
@article{Baddour_2026,
  title = {Spatial and Single-Cell Mapping Reveals Valvular Interstitial Cell and Macrophage Sex Differences in Calcific Aortic Valve Disease},
  volume = {46},
  ISSN = {1524-4636},
  url = {http://dx.doi.org/10.1161/atvbaha.126.324694},
  DOI = {10.1161/atvbaha.126.324694},
  number = {7},
  journal = {Arteriosclerosis, Thrombosis, and Vascular Biology},
  publisher = {Ovid Technologies (Wolters Kluwer Health)},
  author = {Baddour, Talia and Ninh, Van K. and Gorashi, Rayyan M. and Peña, Rene and King, Kevin R. and Aguado, Brian A.},
  year = {2026},
  month = July
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB