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spatial ATAC-seq

Mouse brain

GSM6753043

bronze Interactive viewer H&E ✓ Verified publication
Mouse brain preview
print(sdata)
SpatialData object
├── Images
│     └── 'tissue_hires': DataArray[cyx] (3, 2334, 2332)
├── Shapes
│     ├── 'epi_spots': GeoDataFrame shape: (9215, 1) (2D shapes)
│     └── 'epi_spots_for_vitessce': GeoDataFrame shape: (9215, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (9215, 22914)
with coordinate systems:
    ▸ 'global', with elements:
        tissue_hires (Images), epi_spots (Shapes), epi_spots_for_vitessce (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("Ek76xy8Hf6OXA1vP0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Ek76xy8Hf6OXA1vP")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download Ek76xy8Hf6OXA1vP0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Ek76xy8Hf6OXA1vP

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Ek76xy8Hf6OXA1vP

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
spatial ATAC-seq
Organism
mouse
Tissue
brain
Modality
Epigenomics
Observations
9,215
Tier
bronze
Resolution
2,332 × 2,334 px
mpp
20.000 µm/px
Size
44.3 MB
Sample ID
GSM6753043
License
NCBI GEO policy
Published
Jan 29, 2023

Cite this dataset

doi.org/10.1038/s41586-023-05795-1 ↗
BibTeX
@article{Zhang_2023,
  title = {Spatial epigenome–transcriptome co-profiling of mammalian tissues},
  volume = {616},
  ISSN = {1476-4687},
  url = {http://dx.doi.org/10.1038/s41586-023-05795-1},
  DOI = {10.1038/s41586-023-05795-1},
  number = {7955},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  author = {Zhang, Di and Deng, Yanxiang and Kukanja, Petra and Agirre, Eneritz and Bartosovic, Marek and Dong, Mingze and Ma, Cong and Ma, Sai and Su, Graham and Bao, Shuozhen and Liu, Yang and Xiao, Yang and Rosoklija, Gorazd B. and Dwork, Andrew J. and Mann, J. John and Leong, Kam W. and Boldrini, Maura and Wang, Liya and Haeussler, Maximilian and Raphael, Benjamin J. and Kluger, Yuval and Castelo-Branco, Gonçalo and Fan, Rong},
  year = {2023},
  month = Mar,
  pages = {113–122}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB