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10x Xenium

Mouse forebrain

GSM8965606

silver Interactive viewer ✓ Verified publication
Mouse forebrain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'morphology_focus': DataTree[cyx] (1, 30860, 39916), (1, 15430, 19958), (1, 7715, 9979), (1, 3857, 4989), (1, 1928, 2494)
│     └── 'morphology_mip': DataTree[cyx] (1, 30860, 39916), (1, 15430, 19958), (1, 7715, 9979), (1, 3857, 4989), (1, 1928, 2494)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (30860, 39916), (15430, 19958), (7715, 9979), (3857, 4989), (1928, 2494)
│     └── 'nucleus_labels': DataTree[yx] (30860, 39916), (15430, 19958), (7715, 9979), (3857, 4989), (1928, 2494)
├── Points
│     └── 'transcripts': DataFrame with shape: (64484322, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (101394, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (101394, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (101394, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (101394, 347)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("S58RknC54s6M26qX0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("S58RknC54s6M26qX")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download S58RknC54s6M26qX0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/S58RknC54s6M26qX

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid S58RknC54s6M26qX

License: NCBI GEO policy

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Metadata

Technology
10x Xenium
Organism
mouse
Tissue
forebrain
Modality
RNA
Observations (cells)
101,394
Transcripts
64,484,322
Tier
silver
Chemistry
Xenium v1
Size
6.0 GB
Sample ID
GSM8965606
License
NCBI GEO policy
Published
Aug 1, 2025

Cite this dataset

doi.org/10.1523/eneuro.0046-25.2025 ↗
BibTeX
@article{Ebert_2025,
  title = {Single-Cell Approaches Define the Murine Leptomeninges: Cortical Brain Interface as a Distinct Cellular Neighborhood Composed of Neural and Non-neural Cell Types},
  volume = {12},
  ISSN = {2373-2822},
  url = {http://dx.doi.org/10.1523/eneuro.0046-25.2025},
  DOI = {10.1523/eneuro.0046-25.2025},
  number = {8},
  journal = {eneuro},
  publisher = {Society for Neuroscience},
  author = {Ebert, Sarah N. and Eisner, Christine and Karamboulas, Konstantina and Bernier, Louis-Philippe and Kaplan, David R. and MacVicar, Brian A. and Miller, Freda D.},
  year = {2025},
  month = Aug,
  pages = {ENEURO.0046–25.2025}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB