Collections / Spatial transcriptomic dissection of intratumoral heterogeneity and microenvironment in sinonasal and skull base adenoid cystic carcinoma
Spatial transcriptomic dissection of intratumoral heterogeneity and microenvironment in sinonasal and skull base adenoid cystic carcinoma
We profiled 6 patients with sinonasal-skull base adenoid cystic carcinoma by spatial transcriptomics (10x Genomics Visium) to characterize intratumoral heterogeneity and the immune landscape.
Datasets6
Size~182 MB
AssayVisium
Samplehuman · nasal cavity
KindOther
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Python · sddb client
from sddb import Catalog
cohort = Catalog().collection("geo-gse342687")
cohort.members # the 6 datasets as a table
print(cohort.licenses()) # check the terms before you download
sdatas = cohort.to_dict() # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/") Python · lamindb
Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.
import lamindb as ln
db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse342687")
coll.ordered_artifacts.to_dataframe() # the 6 members, ordered
# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()] Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse342687 --dest data/ Licenses: 6 NCBI GEO policy
Member datasets · 6
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