Collections / Comparative Eye Transcriptome Atlas

Comparative Eye Transcriptome Atlas

The Comparative Eye Transcriptome Atlas provides transcriptomic resources to study retinal evolution and physiology across non-mammalian vertebrates. We profiled retinas from four species using two complementary high-throughput approaches. Eight 10x Genomics Visium spatial transcriptomics datasets were generated from Anolis carolinensis (n = 2), Taeniopygia guttata (n = 4), Columba livia (n = 1), and Gallus gallus (n = 1), capturing spatially resolved gene expression with matched histology images. In parallel, six 10x Genomics Chromium Single Cell 3′ RNA-seq datasets were obtained from zebra finch (T. guttata) retinas to resolve cell-type–specific transcriptomes. Raw sequencing data (FASTQ) and processed outputs from SpaceRanger (Visium) and CellRanger (Chromium) are provided. Downstream integrated and annotated datasets can be explored interactively at https://linlab.au.dk/Damsgaard_lab/CETA/ and full Seurat objects are available on request.

Datasets4
Size~4.5 GB
AssayVisium
Samplezebra finch · retina
KindOther
Flag a data issue
PMID:41565811 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse309408")
cohort.members        # the 4 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse309408")
coll.ordered_artifacts.to_dataframe()   # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse309408 --dest data/

Licenses: 4 NCBI GEO policy

Open in Vitessce
Visium
Zebra finch retina
GSM9266974
zebra finch retina 1.1 GB 777 spots silver NCBI GEO policy
TechnologyVisium
Organismzebra finch
Tissueretina
Size1.1 GB
Spots777
silver NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Zebra finch retina
GSM9266976
zebra finch retina 1.1 GB 479 spots silver NCBI GEO policy
TechnologyVisium
Organismzebra finch
Tissueretina
Size1.1 GB
Spots479
silver NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Zebra finch retina
GSM9266973
zebra finch retina 1.2 GB 1,025 spots silver NCBI GEO policy
TechnologyVisium
Organismzebra finch
Tissueretina
Size1.2 GB
Spots1,025
silver NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Zebra finch retina
GSM9266975
zebra finch retina 1.1 GB 1,109 spots silver NCBI GEO policy
TechnologyVisium
Organismzebra finch
Tissueretina
Size1.1 GB
Spots1,109
silver NCBI GEO policy Open in Vitessce

Cite this collection

No linked publication found — please cite the data source.