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Visium

Mouse spleen

GSM6042729

bronze Interactive viewer H&E lymphocytic choriomeningitis Provisional
Mouse spleen preview
print(sdata)
SpatialData object
├── Images
│     └── 'GSM6042729_Round1_D1_Day21_CD4depl_hires_image': DataArray[cyx] (3, 1952, 2000)
├── Shapes
│     └── 'GSM6042729_Round1_D1_Day21_CD4depl': GeoDataFrame shape: (2495, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2495, 32285)
with coordinate systems:
    ▸ 'GSM6042729_Round1_D1_Day21_CD4depl', with elements:
        GSM6042729_Round1_D1_Day21_CD4depl_hires_image (Images), GSM6042729_Round1_D1_Day21_CD4depl (Shapes)
    ▸ 'GSM6042729_Round1_D1_Day21_CD4depl_downscaled_hires', with elements:
        GSM6042729_Round1_D1_Day21_CD4depl_hires_image (Images), GSM6042729_Round1_D1_Day21_CD4depl (Shapes)
    ▸ 'GSM6042729_Round1_D1_Day21_CD4depl_downscaled_lowres', with elements:
        GSM6042729_Round1_D1_Day21_CD4depl (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("Lci0wMZ9zEDG7WHH0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Lci0wMZ9zEDG7WHH")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download Lci0wMZ9zEDG7WHH0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Lci0wMZ9zEDG7WHH

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Lci0wMZ9zEDG7WHH

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
mouse
Tissue
spleen
Condition
lymphocytic choriomeningitis
Modality
RNA
Observations (spots)
2,495
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,952 px
mpp
3.617 µm/px
Size
34.2 MB
Sample ID
GSM6042729
License
NCBI GEO policy
Published
Nov 29, 2022

Cite this dataset

doi.org/10.1016/j.celrep.2022.111736 ↗
BibTeX
@article{Topchyan_2022,
  title = {Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection},
  volume = {41},
  ISSN = {2211-1247},
  url = {http://dx.doi.org/10.1016/j.celrep.2022.111736},
  DOI = {10.1016/j.celrep.2022.111736},
  number = {9},
  journal = {Cell Reports},
  publisher = {Elsevier BV},
  author = {Topchyan, Paytsar and Zander, Ryan and Kasmani, Moujtaba Y. and Nguyen, Christine and Brown, Ashley and Lin, Siying and Burns, Robert and Cui, Weiguo},
  year = {2022},
  month = Nov,
  pages = {111736}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB