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Visium

Human skin of body

NCBI464

silver Interactive viewer H&E psoriasis ✓ Verified publication
Human skin of body preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI464_full_image': DataTree[cyx] (3, 8126, 8192), (3, 4063, 4096), (3, 2031, 2048), (3, 1015, 1024)
├── Shapes
│     └── 'NCBI464_spots': GeoDataFrame shape: (1979, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1979, 19850)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI464_full_image (Images), NCBI464_spots (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("sFfan0IpZozZGwDu0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("sFfan0IpZozZGwDu")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download sFfan0IpZozZGwDu0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/sFfan0IpZozZGwDu

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid sFfan0IpZozZGwDu

License: CC BY-NC-SA 4.0 (noncommercial)

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Metadata

Technology
Visium
Organism
human
Tissue
skin of body
Condition
psoriasis
Modality
RNA
Observations (spots)
1,979
Tier
silver
Chemistry
Visium v1
Resolution
8,192 × 8,126 px
mpp
1.023 µm/px
Size
105 MB
Sample ID
NCBI464
License
CC BY-NC-SA 4.0 NonCommercial
Published
Nov 14, 2022

Cite this dataset

doi.org/10.1038/s41467-022-35319-w ↗
BibTeX
@article{Sch_bitz_2022,
  title = {Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases},
  volume = {13},
  ISSN = {2041-1723},
  url = {http://dx.doi.org/10.1038/s41467-022-35319-w},
  DOI = {10.1038/s41467-022-35319-w},
  number = {1},
  journal = {Nature Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Schäbitz, A. and Hillig, C. and Mubarak, M. and Jargosch, M. and Farnoud, A. and Scala, E. and Kurzen, N. and Pilz, A. C. and Bhalla, N. and Thomas, J. and Stahle, M. and Biedermann, T. and Schmidt-Weber, C. B. and Theis, F. and Garzorz-Stark, N. and Eyerich, K. and Menden, M. P. and Eyerich, S.},
  year = {2022},
  month = Dec
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB