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Visium

Human prostate gland

GSM8558007

bronze Interactive viewer H&E prostate cancer Provisional
Human prostate gland preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8558007_NEADT_11_hires_image': DataArray[cyx] (3, 2000, 1334)
│     └── 'GSM8558007_NEADT_11_lowres_image': DataArray[cyx] (3, 600, 400)
├── Shapes
│     └── 'GSM8558007_NEADT_11': GeoDataFrame shape: (4401, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4401, 33538)
with coordinate systems:
    ▸ 'GSM8558007_NEADT_11', with elements:
        GSM8558007_NEADT_11_hires_image (Images), GSM8558007_NEADT_11_lowres_image (Images), GSM8558007_NEADT_11 (Shapes)
    ▸ 'GSM8558007_NEADT_11_downscaled_hires', with elements:
        GSM8558007_NEADT_11_hires_image (Images), GSM8558007_NEADT_11 (Shapes)
    ▸ 'GSM8558007_NEADT_11_downscaled_lowres', with elements:
        GSM8558007_NEADT_11_lowres_image (Images), GSM8558007_NEADT_11 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("DzKUGMARKVO2ha4v0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("DzKUGMARKVO2ha4v")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download DzKUGMARKVO2ha4v0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/DzKUGMARKVO2ha4v

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid DzKUGMARKVO2ha4v

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
prostate gland
Condition
prostate cancer
Modality
RNA
Observations (spots)
4,401
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,334 × 2,000 px
mpp
5.541 µm/px
Size
56.6 MB
Sample ID
GSM8558007
License
NCBI GEO policy
Published
Oct 29, 2024

Cite this dataset

doi.org/10.1038/s41467-024-54364-1 ↗
BibTeX
@article{Kiviaho_2024,
  title = {Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer},
  volume = {15},
  ISSN = {2041-1723},
  url = {http://dx.doi.org/10.1038/s41467-024-54364-1},
  DOI = {10.1038/s41467-024-54364-1},
  number = {1},
  journal = {Nature Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Kiviaho, Antti and Eerola, Sini K. and Kallio, Heini M. L. and Andersen, Maria K. and Hoikka, Miina and Tiihonen, Aliisa M. and Salonen, Iida and Spotbeen, Xander and Giesen, Alexander and Parker, Charles T. A. and Taavitsainen, Sinja and Hantula, Olli and Marttinen, Mikael and Hermelo, Ismaïl and Ismail, Mazlina and Midtbust, Elise and Wess, Maximilian and Devlies, Wout and Sharma, Abhibhav and Krossa, Sebastian and Häkkinen, Tomi and Afyounian, Ebrahim and Vandereyken, Katy and Kint, Sam and Kesseli, Juha and Tolonen, Teemu and Tammela, Teuvo L. J. and Viset, Trond and Størkersen, Øystein and Giskeødegård, Guro F. and Rye, Morten B. and Murtola, Teemu and Erickson, Andrew and Latonen, Leena and Bova, G. Steven and Mills, Ian G. and Joniau, Steven and Swinnen, Johannes V. and Voet, Thierry and Mirtti, Tuomas and Attard, Gerhardt and Claessens, Frank and Visakorpi, Tapio and Rautajoki, Kirsi J. and Tessem, May-Britt and Urbanucci, Alfonso and Nykter, Matti},
  year = {2024},
  month = Nov
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB