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Visium

Human pancreas

GSM8915497

bronze Interactive viewer H&E pancreatic ductal adenocarcinoma Provisional
Human pancreas preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8915497_PDAC04_hires_image': DataArray[cyx] (3, 1215, 2000)
│     └── 'GSM8915497_PDAC04_lowres_image': DataArray[cyx] (3, 365, 600)
├── Shapes
│     └── 'GSM8915497_PDAC04': GeoDataFrame shape: (1142, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1142, 17943)
with coordinate systems:
    ▸ 'GSM8915497_PDAC04', with elements:
        GSM8915497_PDAC04_hires_image (Images), GSM8915497_PDAC04_lowres_image (Images), GSM8915497_PDAC04 (Shapes)
    ▸ 'GSM8915497_PDAC04_downscaled_hires', with elements:
        GSM8915497_PDAC04_hires_image (Images), GSM8915497_PDAC04 (Shapes)
    ▸ 'GSM8915497_PDAC04_downscaled_lowres', with elements:
        GSM8915497_PDAC04_lowres_image (Images), GSM8915497_PDAC04 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("qEP9pd4LlyKeufe20000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("qEP9pd4LlyKeufe2")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download qEP9pd4LlyKeufe20000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/qEP9pd4LlyKeufe2

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid qEP9pd4LlyKeufe2

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
pancreas
Condition
pancreatic ductal adenocarcinoma
Modality
RNA
Observations (spots)
1,142
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,215 px
mpp
5.660 µm/px
Size
2.6 MB
Sample ID
GSM8915497
License
NCBI GEO policy
Published
Jun 16, 2025

Cite this dataset

doi.org/10.1172/jci.insight.191595 ↗
BibTeX
@article{Lyman_2025,
  title = {Spatial proteomics and transcriptomics reveal early immune cell organization in pancreatic intraepithelial neoplasia},
  volume = {10},
  ISSN = {2379-3708},
  url = {http://dx.doi.org/10.1172/jci.insight.191595},
  DOI = {10.1172/jci.insight.191595},
  number = {15},
  journal = {JCI Insight},
  publisher = {American Society for Clinical Investigation},
  author = {Lyman, Melissa R. and Mitchell, Jacob T. and Raghavan, Sidharth and Kagohara, Luciane T. and Huff, Amanda L. and Haldar, Saurav D. and Shin, Sarah M. and Guinn, Samantha and Barrett, Benjamin and Longway, Gabriella and Hernandez, Alexei and Coyne, Erin M. and Yuan, Xuan and Andaloori, Lalitya and Lai, Jiaying and Liu, Yun Zhou and Karchin, Rachel and Gupta, Anuj and Kiemen, Ashley L. and Forjaz, André and Wirtz, Denis and Wu, Pei-Hsun and Deshpande, Atul and Lee, Jae W. and Armstrong, Todd D. and Azad, Nilofer S. and Zimmerman, Jacquelyn W. and Wood, Laura D. and Anders, Robert A. and Thompson, Elizabeth D. and Jaffee, Elizabeth M. and Fertig, Elana J. and Ho, Won Jin and Zaidi, Neeha},
  year = {2025},
  month = June
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB