← All datasets
Visium

Human pancreas

GSM8973760

bronze Interactive viewer H&E type 1 diabetes mellitus Provisional
Human pancreas preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8973760_HPAP123_Pancreas_hires_image': DataArray[cyx] (3, 2000, 1507)
│     └── 'GSM8973760_HPAP123_Pancreas_lowres_image': DataArray[cyx] (3, 600, 452)
├── Shapes
│     └── 'GSM8973760_HPAP123_Pancreas': GeoDataFrame shape: (4951, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4951, 18085)
with coordinate systems:
    ▸ 'GSM8973760_HPAP123_Pancreas', with elements:
        GSM8973760_HPAP123_Pancreas_hires_image (Images), GSM8973760_HPAP123_Pancreas_lowres_image (Images), GSM8973760_HPAP123_Pancreas (Shapes)
    ▸ 'GSM8973760_HPAP123_Pancreas_downscaled_hires', with elements:
        GSM8973760_HPAP123_Pancreas_hires_image (Images), GSM8973760_HPAP123_Pancreas (Shapes)
    ▸ 'GSM8973760_HPAP123_Pancreas_downscaled_lowres', with elements:
        GSM8973760_HPAP123_Pancreas_lowres_image (Images), GSM8973760_HPAP123_Pancreas (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("lolqf7actka79AQa0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("lolqf7actka79AQa")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download lolqf7actka79AQa0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/lolqf7actka79AQa

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid lolqf7actka79AQa

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
pancreas
Condition
type 1 diabetes mellitus
Modality
RNA
Observations (spots)
4,951
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,507 × 2,000 px
mpp
7.605 µm/px
Size
57.4 MB
Sample ID
GSM8973760
License
NCBI GEO policy
Published
Jun 23, 2025

Cite this dataset

doi.org/10.1101/2025.05.19.654940 ↗
BibTeX
@article{Medina_Serpas_2025,
  title = {Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes},
  url = {http://dx.doi.org/10.1101/2025.05.19.654940},
  DOI = {10.1101/2025.05.19.654940},
  publisher = {openRxiv},
  author = {Medina-Serpas, Miguel A. and Brusko, Maigan and Golden, Gregory J. and Campbell-Thompson, Martha and Rogers, Trevor and Posgai, Amanda L. and Luning Prak, Eline T. and Liu, Chengyang and Kaestner, Klaus H. and Naji, Ali and Betts, Michael R. and McIntyre, Lauren M. and Atkinson, Mark A. and Brusko, Todd M.},
  year = {2025},
  month = May
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB