Visium

Human neocortex

GSM9643336

silver Interactive viewer H&E ✓ Verified publication

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print(sdata)

SpatialData object
├── Images
│     ├── 'GSM9643336_KS169_D35_full_image': DataTree[cyx] (3, 3000, 3000), (3, 1500, 1500), (3, 750, 750), (3, 375, 375), (3, 187, 187)
│     ├── 'GSM9643336_KS169_D35_hires_image': DataArray[cyx] (3, 3000, 3000)
│     └── 'GSM9643336_KS169_D35_lowres_image': DataArray[cyx] (3, 600, 600)
├── Shapes
│     └── 'GSM9643336_KS169_D35': GeoDataFrame shape: (1859, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1859, 18085)
with coordinate systems:
    ▸ 'GSM9643336_KS169_D35', with elements:
        GSM9643336_KS169_D35_full_image (Images), GSM9643336_KS169_D35_hires_image (Images), GSM9643336_KS169_D35_lowres_image (Images), GSM9643336_KS169_D35 (Shapes)
    ▸ 'GSM9643336_KS169_D35_downscaled_hires', with elements:
        GSM9643336_KS169_D35_hires_image (Images), GSM9643336_KS169_D35 (Shapes)
    ▸ 'GSM9643336_KS169_D35_downscaled_lowres', with elements:
        GSM9643336_KS169_D35_lowres_image (Images), GSM9643336_KS169_D35 (Shapes)

Install (Python 3.12+) Docs →

Python · sddb client

from sddb import Catalog

ds = Catalog().dataset("ZOZz7DxoT2LuW3oU0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)

Install (Python 3.12+) Docs →

Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("ZOZz7DxoT2LuW3oU")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path

Install (Python 3.12+) Docs →

Shell

# sddb client: download the .zarr into data/
sddb-cli download ZOZz7DxoT2LuW3oU0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/ZOZz7DxoT2LuW3oU

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid ZOZz7DxoT2LuW3oU

Install (Python 3.12+) Docs →

License: NCBI GEO policy

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Part of collection

Polarized neocortical organoids with areal signatures upon the formation of anterior and posterior organizers. [Spatial Transcriptomics]→

3 datasets · time course

Metadata

Technology: Visium
Organism: human
Tissue: neocortex
Modality: RNA
Observations (spots): 1,859
Tier: silver
Chemistry: Visium CytAssist v2
Resolution: 3,000 × 3,000 px
mpp: 4.344 µm/px
Size: 66.5 MB
Sample ID: GSM9643336
License: NCBI GEO policy
Published: Sep 9, 2026

Cite this dataset

doi.org/10.1016/j.stem.2026.07.014 ↗

BibTeX

@article{Tsai_2026,
  title = {Morphogen-guided neocortical organoids with anteroposterior areal identity},
  volume = {33},
  ISSN = {1934-5909},
  url = {http://dx.doi.org/10.1016/j.stem.2026.07.014},
  DOI = {10.1016/j.stem.2026.07.014},
  number = {9},
  journal = {Cell Stem Cell},
  publisher = {Elsevier BV},
  author = {Tsai, Yuan-Chen and Ozaki, Hajime and Almet, Axel A. and Fleming, Isabel and Nie, Caihao and Luo, Songhao and Wang, Xinyi and Shiraiwa, Kaori and Noh, Matthew Jung Min and Trejo, Sunnyana and Sugita, Bret Kiyoshi and Dalal, Jiya and Gonzalez, Ruben Alberto and De Jesus, Briana and Branco, Nate and Chen, Gregory Li-Min and Gandal, Michael J. and Nie, Qing and Watanabe, Momoko},
  year = {2026},
  month = Sept,
  pages = {1540–1552.e9}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB