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Visium

Human nasal cavity

GSM9087751

bronze Interactive viewer H&E head and neck squamous cell carcinoma Provisional
Human nasal cavity preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9087751_CK17-25_hires_image': DataArray[cyx] (3, 1923, 2000)
│     └── 'GSM9087751_CK17-25_lowres_image': DataArray[cyx] (3, 577, 600)
├── Shapes
│     └── 'GSM9087751_CK17-25': GeoDataFrame shape: (2945, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2945, 17943)
with coordinate systems:
    ▸ 'GSM9087751_CK17-25', with elements:
        GSM9087751_CK17-25_hires_image (Images), GSM9087751_CK17-25_lowres_image (Images), GSM9087751_CK17-25 (Shapes)
    ▸ 'GSM9087751_CK17-25_downscaled_hires', with elements:
        GSM9087751_CK17-25_hires_image (Images), GSM9087751_CK17-25 (Shapes)
    ▸ 'GSM9087751_CK17-25_downscaled_lowres', with elements:
        GSM9087751_CK17-25_lowres_image (Images), GSM9087751_CK17-25 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("kHZZW9w5YXPaEI0G0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("kHZZW9w5YXPaEI0G")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download kHZZW9w5YXPaEI0G0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/kHZZW9w5YXPaEI0G

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid kHZZW9w5YXPaEI0G

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
nasal cavity
Condition
head and neck squamous cell carcinoma
Modality
RNA
Observations (spots)
2,945
Tier
bronze
Chemistry
Visium v1
Resolution
2,000 × 1,923 px
mpp
3.752 µm/px
Size
56.7 MB
Sample ID
GSM9087751
License
NCBI GEO policy
Published
Feb 16, 2026

Cite this dataset

doi.org/10.1158/1078-0432.ccr-25-2300 ↗
BibTeX
@article{Golfinos_Owens_2026,
  title = {Integrated Single-Cell and Spatial Analysis Reveals Context-Dependent Myeloid–T Cell Interactions in Response to Immune Checkpoint Blockade in Head and Neck Cancer},
  volume = {32},
  ISSN = {1557-3265},
  url = {http://dx.doi.org/10.1158/1078-0432.ccr-25-2300},
  DOI = {10.1158/1078-0432.ccr-25-2300},
  number = {12},
  journal = {Clinical Cancer Research},
  publisher = {American Association for Cancer Research (AACR)},
  author = {Golfinos-Owens, Athena E. and Lozar, Taja and Khatri, Parth and Johns, Evan D. and Hu, Rong and Harari, Paul M. and Lambert, Paul F. and Fitzpatrick, Megan B. and Dinh, Huy Q.},
  year = {2026},
  month = Mar,
  pages = {2494–2507}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB