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Visium

Human mucosa

GSM8633893

bronze Interactive viewer H&E head and neck squamous cell carcinoma Provisional
Human mucosa preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8633893_21_01569_LI_SING_hires_image': DataArray[cyx] (3, 2000, 1979)
│     └── 'GSM8633893_21_01569_LI_SING_lowres_image': DataArray[cyx] (3, 600, 594)
├── Shapes
│     └── 'GSM8633893_21_01569_LI_SING': GeoDataFrame shape: (1359, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1359, 36601)
with coordinate systems:
    ▸ 'GSM8633893_21_01569_LI_SING', with elements:
        GSM8633893_21_01569_LI_SING_hires_image (Images), GSM8633893_21_01569_LI_SING_lowres_image (Images), GSM8633893_21_01569_LI_SING (Shapes)
    ▸ 'GSM8633893_21_01569_LI_SING_downscaled_hires', with elements:
        GSM8633893_21_01569_LI_SING_hires_image (Images), GSM8633893_21_01569_LI_SING (Shapes)
    ▸ 'GSM8633893_21_01569_LI_SING_downscaled_lowres', with elements:
        GSM8633893_21_01569_LI_SING_lowres_image (Images), GSM8633893_21_01569_LI_SING (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("fc0RQypHJ9SGiekY0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("fc0RQypHJ9SGiekY")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download fc0RQypHJ9SGiekY0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/fc0RQypHJ9SGiekY

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid fc0RQypHJ9SGiekY

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
mucosa
Condition
head and neck squamous cell carcinoma
Modality
RNA
Observations (spots)
1,359
Tier
bronze
Chemistry
Visium v1
Resolution
1,979 × 2,000 px
mpp
3.263 µm/px
Size
20.7 MB
Sample ID
GSM8633893
License
NCBI GEO policy
Published
Nov 20, 2024

Cite this dataset

doi.org/10.1002/jmv.29386 ↗
BibTeX
@article{Lee_2024,
  title = {Deciphering head and neck cancer microenvironment: Single‐cell and spatial transcriptomics reveals human papillomavirus‐associated differences},
  volume = {96},
  ISSN = {1096-9071},
  url = {http://dx.doi.org/10.1002/jmv.29386},
  DOI = {10.1002/jmv.29386},
  number = {1},
  journal = {Journal of Medical Virology},
  publisher = {Wiley},
  author = {Lee, Hansong and Park, Sohee and Yun, Ju Hyun and Seo, Chorong and Ahn, Ji Mi and Cha, Hyun‐Young and Shin, Yoo Seob and Park, Hae Ryoun and Lee, Dongjun and Roh, Jin and Heo, Hye Jin and Baek, Seung Eun and Kim, Eun Kyoung and Lee, Hae Seul and Kim, Chul‐Ho and Kim, Yun Hak and Jang, Jeon Yeob},
  year = {2024},
  month = Jan
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB