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Visium

Human medulla oblongata

GSM8608421

bronze Interactive viewer H&E diffuse intrinsic pontine glioma Provisional
Human medulla oblongata preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8608421_C1_VLP45_hires_image': DataArray[cyx] (3, 2000, 1974)
│     └── 'GSM8608421_C1_VLP45_lowres_image': DataArray[cyx] (3, 600, 592)
├── Shapes
│     └── 'GSM8608421_C1_VLP45': GeoDataFrame shape: (2712, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2712, 17943)
with coordinate systems:
    ▸ 'GSM8608421_C1_VLP45', with elements:
        GSM8608421_C1_VLP45_hires_image (Images), GSM8608421_C1_VLP45_lowres_image (Images), GSM8608421_C1_VLP45 (Shapes)
    ▸ 'GSM8608421_C1_VLP45_downscaled_hires', with elements:
        GSM8608421_C1_VLP45_hires_image (Images), GSM8608421_C1_VLP45 (Shapes)
    ▸ 'GSM8608421_C1_VLP45_downscaled_lowres', with elements:
        GSM8608421_C1_VLP45_lowres_image (Images), GSM8608421_C1_VLP45 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("isZou4MAjPTrnVq40000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("isZou4MAjPTrnVq4")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download isZou4MAjPTrnVq40000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/isZou4MAjPTrnVq4

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid isZou4MAjPTrnVq4

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
medulla oblongata
Condition
diffuse intrinsic pontine glioma
Modality
RNA
Observations (spots)
2,712
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,974 × 2,000 px
mpp
3.268 µm/px
Size
36.2 MB
Sample ID
GSM8608421
License
NCBI GEO policy
Published
Nov 18, 2024

Cite this dataset

doi.org/10.1186/s40478-025-01952-x ↗
BibTeX
@article{Kordowski_2025,
  title = {Spatial analysis of a complete DIPG-infiltrated brainstem reveals novel ligand-receptor mediators of tumour-to-TME crosstalk},
  volume = {13},
  ISSN = {2051-5960},
  url = {http://dx.doi.org/10.1186/s40478-025-01952-x},
  DOI = {10.1186/s40478-025-01952-x},
  number = {1},
  journal = {Acta Neuropathologica Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Kordowski, Anja and Mulay, Onkar and Tan, Xiao and Vo, Tuan and Baumgartner, Ulrich and Maybury, Mellissa K. and Hassall, Timothy and Harris, Lachlan and Nguyen, Quan and Day, Bryan W.},
  year = {2025},
  month = Feb
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB