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Visium

Mouse mammary gland

GSM8428408

bronze Interactive viewer H&E breast cancer Provisional
Mouse mammary gland preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8428408_09.9_627_TM_V11Y03-083_A_hires_image': DataArray[cyx] (3, 1256, 2000)
│     └── 'GSM8428408_09.9_627_TM_V11Y03-083_A_lowres_image': DataArray[cyx] (3, 377, 600)
├── Shapes
│     └── 'GSM8428408_09.9_627_TM_V11Y03-083_A': GeoDataFrame shape: (2596, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2596, 19465)
with coordinate systems:
    ▸ 'GSM8428408_09.9_627_TM_V11Y03-083_A', with elements:
        GSM8428408_09.9_627_TM_V11Y03-083_A_hires_image (Images), GSM8428408_09.9_627_TM_V11Y03-083_A_lowres_image (Images), GSM8428408_09.9_627_TM_V11Y03-083_A (Shapes)
    ▸ 'GSM8428408_09.9_627_TM_V11Y03-083_A_downscaled_hires', with elements:
        GSM8428408_09.9_627_TM_V11Y03-083_A_hires_image (Images), GSM8428408_09.9_627_TM_V11Y03-083_A (Shapes)
    ▸ 'GSM8428408_09.9_627_TM_V11Y03-083_A_downscaled_lowres', with elements:
        GSM8428408_09.9_627_TM_V11Y03-083_A_lowres_image (Images), GSM8428408_09.9_627_TM_V11Y03-083_A (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("XK5EVtzRrBKC2TCF0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("XK5EVtzRrBKC2TCF")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download XK5EVtzRrBKC2TCF0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/XK5EVtzRrBKC2TCF

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid XK5EVtzRrBKC2TCF

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
mouse
Tissue
mammary gland
Condition
breast cancer
Modality
RNA
Observations (spots)
2,596
Tier
bronze
Chemistry
Visium v1
Resolution
2,000 × 1,256 px
mpp
5.665 µm/px
Size
22.9 MB
Sample ID
GSM8428408
License
NCBI GEO policy
Published
Aug 4, 2024

Cite this dataset

doi.org/10.1186/s13046-025-03353-3 ↗
BibTeX
@article{Bertolazzi_2025,
  title = {Extraction of a stromal metastatic gene signature in breast cancer via spatial profiling},
  volume = {44},
  ISSN = {1756-9966},
  url = {http://dx.doi.org/10.1186/s13046-025-03353-3},
  DOI = {10.1186/s13046-025-03353-3},
  number = {1},
  journal = {Journal of Experimental & Clinical Cancer Research},
  publisher = {Springer Science and Business Media LLC},
  author = {Bertolazzi, Giorgio and Cancila, Valeria and Vacca, Davide and Belmonte, Beatrice and Lecis, Daniele and Moghaddam, Parsa Sirati and Di Napoli, Arianna and Colombo, Mario Paolo and Pruneri, Giancarlo and Del Sal, Giannino and Scita, Giorgio and Fassan, Matteo and Vecchione, Andrea and Bicciato, Silvio and Tripodo, Claudio},
  year = {2025},
  month = Mar
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB