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Visium

Human mammary gland

GSM6177603

bronze Interactive viewer H&E breast carcinoma Provisional
Human mammary gland preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM6177603_NYU_BRCA2_Vis_processed_hires_image': DataArray[cyx] (3, 1964, 2000)
│     └── 'GSM6177603_NYU_BRCA2_Vis_processed_lowres_image': DataArray[cyx] (3, 589, 600)
├── Shapes
│     └── 'GSM6177603_NYU_BRCA2_Vis_processed': GeoDataFrame shape: (2346, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2346, 33538)
with coordinate systems:
    ▸ 'GSM6177603_NYU_BRCA2_Vis_processed', with elements:
        GSM6177603_NYU_BRCA2_Vis_processed_hires_image (Images), GSM6177603_NYU_BRCA2_Vis_processed_lowres_image (Images), GSM6177603_NYU_BRCA2_Vis_processed (Shapes)
    ▸ 'GSM6177603_NYU_BRCA2_Vis_processed_downscaled_hires', with elements:
        GSM6177603_NYU_BRCA2_Vis_processed_hires_image (Images), GSM6177603_NYU_BRCA2_Vis_processed (Shapes)
    ▸ 'GSM6177603_NYU_BRCA2_Vis_processed_downscaled_lowres', with elements:
        GSM6177603_NYU_BRCA2_Vis_processed_lowres_image (Images), GSM6177603_NYU_BRCA2_Vis_processed (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("clyHb1Wl33HF1pLB0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("clyHb1Wl33HF1pLB")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download clyHb1Wl33HF1pLB0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/clyHb1Wl33HF1pLB

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid clyHb1Wl33HF1pLB

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
mammary gland
Condition
breast carcinoma
Modality
RNA
Observations (spots)
2,346
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,964 px
mpp
3.435 µm/px
Size
34.3 MB
Sample ID
GSM6177603
License
NCBI GEO policy
Published
Aug 5, 2022

Cite this dataset

doi.org/10.1038/s41588-022-01141-9 ↗
BibTeX
@article{Barkley_2022,
  title = {Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment},
  volume = {54},
  ISSN = {1546-1718},
  url = {http://dx.doi.org/10.1038/s41588-022-01141-9},
  DOI = {10.1038/s41588-022-01141-9},
  number = {8},
  journal = {Nature Genetics},
  publisher = {Springer Science and Business Media LLC},
  author = {Barkley, Dalia and Moncada, Reuben and Pour, Maayan and Liberman, Deborah A. and Dryg, Ian and Werba, Gregor and Wang, Wei and Baron, Maayan and Rao, Anjali and Xia, Bo and França, Gustavo S. and Weil, Alejandro and Delair, Deborah F. and Hajdu, Cristina and Lund, Amanda W. and Osman, Iman and Yanai, Itai},
  year = {2022},
  month = Aug,
  pages = {1192–1201}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB