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Visium

Human lymph node

GSM8500539

bronze Interactive viewer H&E diffuse large B-cell lymphoma Provisional
Human lymph node preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8500539_Cap.area6_DLBCL_V2_hires_image': DataArray[cyx] (3, 1962, 2000)
│     └── 'GSM8500539_Cap.area6_DLBCL_V2_lowres_image': DataArray[cyx] (3, 589, 600)
├── Shapes
│     └── 'GSM8500539_Cap.area6_DLBCL_V2': GeoDataFrame shape: (4992, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4992, 18085)
with coordinate systems:
    ▸ 'GSM8500539_Cap.area6_DLBCL_V2', with elements:
        GSM8500539_Cap.area6_DLBCL_V2_hires_image (Images), GSM8500539_Cap.area6_DLBCL_V2_lowres_image (Images), GSM8500539_Cap.area6_DLBCL_V2 (Shapes)
    ▸ 'GSM8500539_Cap.area6_DLBCL_V2_downscaled_hires', with elements:
        GSM8500539_Cap.area6_DLBCL_V2_hires_image (Images), GSM8500539_Cap.area6_DLBCL_V2 (Shapes)
    ▸ 'GSM8500539_Cap.area6_DLBCL_V2_downscaled_lowres', with elements:
        GSM8500539_Cap.area6_DLBCL_V2_lowres_image (Images), GSM8500539_Cap.area6_DLBCL_V2 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("WylO2X32Aztw8UNu0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("WylO2X32Aztw8UNu")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download WylO2X32Aztw8UNu0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/WylO2X32Aztw8UNu

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid WylO2X32Aztw8UNu

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
lymph node
Condition
diffuse large B-cell lymphoma
Modality
RNA
Observations (spots)
4,992
Tier
bronze
Chemistry
Visium v1
Resolution
2,000 × 1,962 px
mpp
3.146 µm/px
Size
122 MB
Sample ID
GSM8500539
License
NCBI GEO policy
Published
Apr 29, 2026

Cite this dataset

doi.org/10.1080/2162402x.2026.2660418 ↗
BibTeX
@article{Diaz_Herrero_2026,
  title = {Spatial transcriptomics unveils immune cellular ecosystems associated with patient survival in diffuse large B-cell lymphoma},
  volume = {15},
  ISSN = {2162-402X},
  url = {http://dx.doi.org/10.1080/2162402x.2026.2660418},
  DOI = {10.1080/2162402x.2026.2660418},
  number = {1},
  journal = {OncoImmunology},
  publisher = {Informa UK Limited},
  author = {Diaz-Herrero, Alba and Pelaez-Prestel, Héctor Fernando and Massenet-Regad, Lucile and Veyssiere, Maëva and Calvani, Julien and Cristinelli, Caterina and Lehmann-Che, Jacqueline and Meignin, Véronique and Thieblemont, Catherine and Blanc, Véronique and Soumelis, Vassili and Tonnerre, Pierre},
  year = {2026},
  month = Apr
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB