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Visium

Mouse lung

GSM6634341

bronze Interactive viewer H&E lung adenocarcinoma Provisional
Mouse lung preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM6634341_DT2_C1_hires_image': DataArray[cyx] (3, 2000, 2000)
│     └── 'GSM6634341_DT2_C1_lowres_image': DataArray[cyx] (3, 600, 600)
├── Shapes
│     └── 'GSM6634341_DT2_C1': GeoDataFrame shape: (3505, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (3505, 30970)
with coordinate systems:
    ▸ 'GSM6634341_DT2_C1', with elements:
        GSM6634341_DT2_C1_hires_image (Images), GSM6634341_DT2_C1_lowres_image (Images), GSM6634341_DT2_C1 (Shapes)
    ▸ 'GSM6634341_DT2_C1_downscaled_hires', with elements:
        GSM6634341_DT2_C1_hires_image (Images), GSM6634341_DT2_C1 (Shapes)
    ▸ 'GSM6634341_DT2_C1_downscaled_lowres', with elements:
        GSM6634341_DT2_C1_lowres_image (Images), GSM6634341_DT2_C1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("JiA6vDXclASZ63420000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("JiA6vDXclASZ6342")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download JiA6vDXclASZ63420000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/JiA6vDXclASZ6342

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid JiA6vDXclASZ6342

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
mouse
Tissue
lung
Condition
lung adenocarcinoma
Modality
RNA
Observations (spots)
3,505
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 2,000 px
mpp
3.730 µm/px
Size
48.9 MB
Sample ID
GSM6634341
License
NCBI GEO policy
Published
May 3, 2023

Cite this dataset

doi.org/10.1038/s41590-023-01504-2 ↗
BibTeX
@article{Glasner_2023,
  title = {Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies},
  volume = {24},
  ISSN = {1529-2916},
  url = {http://dx.doi.org/10.1038/s41590-023-01504-2},
  DOI = {10.1038/s41590-023-01504-2},
  number = {6},
  journal = {Nature Immunology},
  publisher = {Springer Science and Business Media LLC},
  author = {Glasner, Ariella and Rose, Samuel A. and Sharma, Roshan and Gudjonson, Herman and Chu, Tinyi and Green, Jesse A. and Rampersaud, Sham and Valdez, Izabella K. and Andretta, Emma S. and Dhillon, Bahawar S. and Schizas, Michail and Dikiy, Stanislav and Mendoza, Alejandra and Hu, Wei and Wang, Zhong-Min and Chaudhary, Ojasvi and Xu, Tianhao and Mazutis, Linas and Rizzuto, Gabrielle and Quintanal-Villalonga, Alvaro and Manoj, Parvathy and de Stanchina, Elisa and Rudin, Charles M. and Pe’er, Dana and Rudensky, Alexander Y.},
  year = {2023},
  month = May,
  pages = {1020–1035}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB