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Visium

Human lung

GSM9485176

bronze Interactive viewer H&E chronic obstructive pulmonary disease Provisional
Human lung preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9485176_COPD2_hires_image': DataArray[cyx] (3, 1916, 2000)
│     └── 'GSM9485176_COPD2_lowres_image': DataArray[cyx] (3, 575, 600)
├── Shapes
│     └── 'GSM9485176_COPD2': GeoDataFrame shape: (1872, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1872, 36601)
with coordinate systems:
    ▸ 'GSM9485176_COPD2', with elements:
        GSM9485176_COPD2_hires_image (Images), GSM9485176_COPD2_lowres_image (Images), GSM9485176_COPD2 (Shapes)
    ▸ 'GSM9485176_COPD2_downscaled_hires', with elements:
        GSM9485176_COPD2_hires_image (Images), GSM9485176_COPD2 (Shapes)
    ▸ 'GSM9485176_COPD2_downscaled_lowres', with elements:
        GSM9485176_COPD2_lowres_image (Images), GSM9485176_COPD2 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("eTBOTHyt9Ju7O4mT0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("eTBOTHyt9Ju7O4mT")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download eTBOTHyt9Ju7O4mT0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/eTBOTHyt9Ju7O4mT

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid eTBOTHyt9Ju7O4mT

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
lung
Condition
chronic obstructive pulmonary disease
Modality
RNA
Observations (spots)
1,872
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,916 px
mpp
3.941 µm/px
Size
11.6 MB
Sample ID
GSM9485176
License
NCBI GEO policy
Published
Sep 16, 2026

Cite this dataset

doi.org/10.1186/s40364-026-00960-w ↗
BibTeX
@article{Syarif_2026,
  title = {Spatial transcriptomics reveals compartment-specific cytotoxic T cell crosstalk with AT2 and goblet cells in advanced COPD},
  volume = {14},
  ISSN = {2050-7771},
  url = {http://dx.doi.org/10.1186/s40364-026-00960-w},
  DOI = {10.1186/s40364-026-00960-w},
  number = {1},
  journal = {Biomarker Research},
  publisher = {Springer Science and Business Media LLC},
  author = {Syarif, Ayu Hutami and Reiter, Bernhard F. E. and Avian, Alexander and Milger, Katrin and Ellmeier, Elena and Hoefler, Gerald and Aigner, Clemens and Benazzo, Alberto and Auner, Sophia and Crnkovic, Slaven and Angiari, Stefano and Polverino, Francesca and Kwapiszewska, Grazyna and Marsh, Leigh M.},
  year = {2026},
  month = June
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB