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Visium

Mouse liver

GSM8285401

bronze Interactive viewer H&E malaria Provisional
Mouse liver preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8285401_C1_hires_image': DataArray[cyx] (3, 2000, 1979)
│     └── 'GSM8285401_C1_lowres_image': DataArray[cyx] (3, 600, 594)
├── Shapes
│     └── 'GSM8285401_C1': GeoDataFrame shape: (2999, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2999, 60646)
with coordinate systems:
    ▸ 'GSM8285401_C1', with elements:
        GSM8285401_C1_hires_image (Images), GSM8285401_C1_lowres_image (Images), GSM8285401_C1 (Shapes)
    ▸ 'GSM8285401_C1_downscaled_hires', with elements:
        GSM8285401_C1_hires_image (Images), GSM8285401_C1 (Shapes)
    ▸ 'GSM8285401_C1_downscaled_lowres', with elements:
        GSM8285401_C1_lowres_image (Images), GSM8285401_C1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("uENTkIpHjr5exTbU0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("uENTkIpHjr5exTbU")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download uENTkIpHjr5exTbU0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/uENTkIpHjr5exTbU

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid uENTkIpHjr5exTbU

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
mouse
Tissue
liver
Condition
malaria
Modality
RNA
Observations (spots)
2,999
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,979 × 2,000 px
mpp
3.503 µm/px
Size
30.1 MB
Sample ID
GSM8285401
License
NCBI GEO policy
Published
Jun 3, 2024

Cite this dataset

doi.org/10.1038/s41467-024-51418-2 ↗
BibTeX
@article{Hildebrandt_2024,
  title = {Host-pathogen interactions in the Plasmodium-infected mouse liver at spatial and single-cell resolution},
  volume = {15},
  ISSN = {2041-1723},
  url = {http://dx.doi.org/10.1038/s41467-024-51418-2},
  DOI = {10.1038/s41467-024-51418-2},
  number = {1},
  journal = {Nature Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Hildebrandt, Franziska and Iturritza, Miren Urrutia and Zwicker, Christian and Vanneste, Bavo and Van Hul, Noémi and Semle, Elisa and Quin, Jaclyn and Pascini, Tales and Saarenpää, Sami and He, Mengxiao and Andersson, Emma R. and Scott, Charlotte L. and Vega-Rodriguez, Joel and Lundeberg, Joakim and Ankarklev, Johan},
  year = {2024},
  month = Aug
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB