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Visium

Human liver

GSM7968251

bronze Interactive viewer H&E hepatoblastoma Provisional
Human liver preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM7968251_HB4_hires_image': DataArray[cyx] (3, 1968, 2000)
│     └── 'GSM7968251_HB4_lowres_image': DataArray[cyx] (3, 591, 600)
├── Shapes
│     └── 'GSM7968251_HB4': GeoDataFrame shape: (3212, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (3212, 17943)
with coordinate systems:
    ▸ 'GSM7968251_HB4', with elements:
        GSM7968251_HB4_hires_image (Images), GSM7968251_HB4_lowres_image (Images), GSM7968251_HB4 (Shapes)
    ▸ 'GSM7968251_HB4_downscaled_hires', with elements:
        GSM7968251_HB4_hires_image (Images), GSM7968251_HB4 (Shapes)
    ▸ 'GSM7968251_HB4_downscaled_lowres', with elements:
        GSM7968251_HB4_lowres_image (Images), GSM7968251_HB4 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("HOIC4HzQzc05BePb0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("HOIC4HzQzc05BePb")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download HOIC4HzQzc05BePb0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/HOIC4HzQzc05BePb

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid HOIC4HzQzc05BePb

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
Spatial transcriptomics of primary human hepatoblastomas→
3 datasets · comparison

Metadata

Technology
Visium
Organism
human
Tissue
liver
Condition
hepatoblastoma
Modality
RNA
Observations (spots)
3,212
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,968 px
mpp
3.683 µm/px
Size
60.9 MB
Sample ID
GSM7968251
License
NCBI GEO policy
Published
Sep 12, 2024

Cite this dataset

doi.org/10.1038/s41467-024-53802-4 ↗
BibTeX
@article{Wu_2024,
  title = {A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma},
  volume = {15},
  ISSN = {2041-1723},
  url = {http://dx.doi.org/10.1038/s41467-024-53802-4},
  DOI = {10.1038/s41467-024-53802-4},
  number = {1},
  journal = {Nature Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Wu, Peng V. and Fish, Matt and Hazard, Florette K. and Zhu, Chunfang and Vennam, Sujay and Walton, Hannah and Wagh, Dhananjay and Coller, John and Przybyl, Joanna and Morri, Maurizio and Neff, Norma and West, Robert B. and Nusse, Roel},
  year = {2024},
  month = Nov
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB