← All datasets
Visium

Human liver

GSE278621

bronze Interactive viewer H&E metabolic dysfunction-associated steatotic liver disease Provisional
Human liver preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8551438_RGL25a_hires_image': DataArray[cyx] (3, 1817, 2000)
│     └── 'GSM8551438_RGL25a_lowres_image': DataArray[cyx] (3, 545, 600)
├── Shapes
│     └── 'GSM8551438_RGL25a': GeoDataFrame shape: (3738, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (3738, 17943)
with coordinate systems:
    ▸ 'GSM8551438_RGL25a', with elements:
        GSM8551438_RGL25a_hires_image (Images), GSM8551438_RGL25a_lowres_image (Images), GSM8551438_RGL25a (Shapes)
    ▸ 'GSM8551438_RGL25a_downscaled_hires', with elements:
        GSM8551438_RGL25a_hires_image (Images), GSM8551438_RGL25a (Shapes)
    ▸ 'GSM8551438_RGL25a_downscaled_lowres', with elements:
        GSM8551438_RGL25a_lowres_image (Images), GSM8551438_RGL25a (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("24sINQJLEWgPMwtD0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("24sINQJLEWgPMwtD")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 24sINQJLEWgPMwtD0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/24sINQJLEWgPMwtD

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 24sINQJLEWgPMwtD

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
liver
Condition
metabolic dysfunction-associated steatotic liver disease
Modality
RNA
Observations (spots)
3,738
Tier
bronze
Chemistry
Visium v1
Resolution
2,000 × 1,817 px
mpp
4.050 µm/px
Size
15.5 MB
Sample ID
GSE278621
License
NCBI GEO policy
Published
Jul 22, 2026

Cite this dataset

doi.org/10.1093/gigascience/giag074 ↗
BibTeX
@article{geo:GSE278621,
  doi = {10.1093/gigascience/giag074},
  title = {GSE278621},
  year = {2026}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB