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Visium

Human kidney

GSM8896254

bronze Interactive viewer H&E clear cell renal carcinoma Provisional
Human kidney preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8896254_sc27T_ST_hires_image': DataArray[cyx] (3, 1750, 2000)
│     └── 'GSM8896254_sc27T_ST_lowres_image': DataArray[cyx] (3, 525, 600)
├── Shapes
│     └── 'GSM8896254_sc27T_ST': GeoDataFrame shape: (4174, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4174, 17943)
with coordinate systems:
    ▸ 'GSM8896254_sc27T_ST', with elements:
        GSM8896254_sc27T_ST_hires_image (Images), GSM8896254_sc27T_ST_lowres_image (Images), GSM8896254_sc27T_ST (Shapes)
    ▸ 'GSM8896254_sc27T_ST_downscaled_hires', with elements:
        GSM8896254_sc27T_ST_hires_image (Images), GSM8896254_sc27T_ST (Shapes)
    ▸ 'GSM8896254_sc27T_ST_downscaled_lowres', with elements:
        GSM8896254_sc27T_ST_lowres_image (Images), GSM8896254_sc27T_ST (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("mg8o3jX0rUxRiyeI0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("mg8o3jX0rUxRiyeI")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download mg8o3jX0rUxRiyeI0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/mg8o3jX0rUxRiyeI

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid mg8o3jX0rUxRiyeI

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
kidney
Condition
clear cell renal carcinoma
Modality
RNA
Observations (spots)
4,174
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,750 px
mpp
4.149 µm/px
Size
38.3 MB
Sample ID
GSM8896254
License
NCBI GEO policy
Published
Apr 23, 2026

Cite this dataset

doi.org/10.1016/j.ccell.2026.05.007 ↗
BibTeX
@article{Vuong_2026,
  title = {Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell carcinoma},
  volume = {44},
  ISSN = {1535-6108},
  url = {http://dx.doi.org/10.1016/j.ccell.2026.05.007},
  DOI = {10.1016/j.ccell.2026.05.007},
  number = {7},
  journal = {Cancer Cell},
  publisher = {Elsevier BV},
  author = {Vuong, Lynda and Cornish, Andrew E. and Pfeil, Jennifer and Khandwala, Yash and Jiang, Hui and Zheng, Doris X.T. and Mascareno, Eduardo A. and Rittenhouse, Nicole and Rappold, Phillip M. and Leibold, Josef and Sabio, Erich A. and Weiss, Kate and Gonzalez, Carlene and Ji, Liangliang and Zhang, Jing and Adlesic, Mojca and Akin, Oguz and Flynn, Jessica and Krishna, Chirag and Lopez Sanmiguel, Andrea and Sager, Rebecca A. and Tan, Tiak J. and Sanchez, Alejandro and Di Natale, Renzo G. and Blum, Kyle A. and Russo, Paul and Coleman, Jonathan A. and Frew, Ian J. and Chowell, Diego and Chen, Ying-Bei and Solit, David B. and Ostrovnaya, Irina and Motzer, Robert J. and Voss, Martin H. and Kotecha, Ritesh R. and Chan, Timothy A. and Jackson, Hartland W. and Kuo, Fengshen and Li, Ming O. and Hakimi, A. Ari},
  year = {2026},
  month = July,
  pages = {1477–1495.e15}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB