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Visium

Human kidney

GSM7974887

bronze Interactive viewer H&E clear cell renal carcinoma Provisional
Human kidney preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM7974887_S2-C_hires_image': DataArray[cyx] (3, 2000, 1968)
│     └── 'GSM7974887_S2-C_lowres_image': DataArray[cyx] (3, 600, 591)
├── Shapes
│     └── 'GSM7974887_S2-C': GeoDataFrame shape: (2258, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2258, 17943)
with coordinate systems:
    ▸ 'GSM7974887_S2-C', with elements:
        GSM7974887_S2-C_hires_image (Images), GSM7974887_S2-C_lowres_image (Images), GSM7974887_S2-C (Shapes)
    ▸ 'GSM7974887_S2-C_downscaled_hires', with elements:
        GSM7974887_S2-C_hires_image (Images), GSM7974887_S2-C (Shapes)
    ▸ 'GSM7974887_S2-C_downscaled_lowres', with elements:
        GSM7974887_S2-C_lowres_image (Images), GSM7974887_S2-C (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("M7zdYIvV1fmS9H9i0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("M7zdYIvV1fmS9H9i")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download M7zdYIvV1fmS9H9i0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/M7zdYIvV1fmS9H9i

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid M7zdYIvV1fmS9H9i

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
kidney
Condition
clear cell renal carcinoma
Modality
RNA
Observations (spots)
2,258
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,968 × 2,000 px
mpp
3.941 µm/px
Size
38.2 MB
Sample ID
GSM7974887
License
NCBI GEO policy
Published
Oct 18, 2024

Cite this dataset

doi.org/10.1158/2159-8290.cd-24-0187 ↗
BibTeX
@article{Bischoff_2024,
  title = {Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma},
  volume = {15},
  ISSN = {2159-8290},
  url = {http://dx.doi.org/10.1158/2159-8290.cd-24-0187},
  DOI = {10.1158/2159-8290.cd-24-0187},
  number = {2},
  journal = {Cancer Discovery},
  publisher = {American Association for Cancer Research (AACR)},
  author = {Bischoff, Megan E. and Shamsaei, Behrouz and Yang, Juechen and Secic, Dina and Vemuri, Bhargav and Reisz, Julie A. and D’Alessandro, Angelo and Bartolacci, Caterina and Adamczak, Rafal and Schmidt, Lucas and Wang, Jiang and Martines, Amelia and Venkat, Jahnavi and Tcheuyap, Vanina Toffessi and Biesiada, Jacek and Behrmann, Catherine A. and Vest, Katherine E. and Brugarolas, James and Scaglioni, Pier Paolo and Plas, David R. and Patra, Krushna C. and Gulati, Shuchi and Landero Figueroa, Julio A. and Meller, Jarek and Cunningham, John T. and Czyzyk-Krzeska, Maria F.},
  year = {2024},
  month = Oct,
  pages = {401–426}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB