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Visium

Human kidney

GSE261545

bronze Interactive viewer H&E diabetic kidney disease Provisional
Human kidney preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8146484_DKD1_hires_image': DataArray[cyx] (3, 2000, 1781)
│     └── 'GSM8146484_DKD1_lowres_image': DataArray[cyx] (3, 600, 534)
├── Shapes
│     └── 'GSM8146484_DKD1': GeoDataFrame shape: (2802, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2802, 18085)
with coordinate systems:
    ▸ 'GSM8146484_DKD1', with elements:
        GSM8146484_DKD1_hires_image (Images), GSM8146484_DKD1_lowres_image (Images), GSM8146484_DKD1 (Shapes)
    ▸ 'GSM8146484_DKD1_downscaled_hires', with elements:
        GSM8146484_DKD1_hires_image (Images), GSM8146484_DKD1 (Shapes)
    ▸ 'GSM8146484_DKD1_downscaled_lowres', with elements:
        GSM8146484_DKD1_lowres_image (Images), GSM8146484_DKD1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("2Px4hjJFRq22eikg0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("2Px4hjJFRq22eikg")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 2Px4hjJFRq22eikg0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/2Px4hjJFRq22eikg

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 2Px4hjJFRq22eikg

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
kidney
Condition
diabetic kidney disease
Modality
RNA
Observations (spots)
2,802
Tier
bronze
Chemistry
Visium v1
Resolution
1,781 × 2,000 px
mpp
3.785 µm/px
Size
62.8 MB
Sample ID
GSE261545
License
NCBI GEO policy
Published
Jun 27, 2024

Cite this dataset

doi.org/10.1016/j.ajpath.2024.06.011 ↗
BibTeX
@article{geo:GSE261545,
  doi = {10.1016/j.ajpath.2024.06.011},
  title = {GSE261545},
  year = {2025}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB