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Visium

Human intestine

MISC47

silver Interactive viewer H&E colon adenocarcinoma ✓ Verified publication
Human intestine preview
print(sdata)
SpatialData object
├── Images
│     └── 'MISC47_full_image': DataTree[cyx] (3, 40228, 33578), (3, 20114, 16789), (3, 10057, 8394), (3, 5028, 4197)
├── Shapes
│     └── 'MISC47_spots': GeoDataFrame shape: (4818, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4818, 19327)
with coordinate systems:
    ▸ 'global', with elements:
        MISC47_full_image (Images), MISC47_spots (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("Za6gMhRyrRrhnKns0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Za6gMhRyrRrhnKns")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download Za6gMhRyrRrhnKns0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Za6gMhRyrRrhnKns

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Za6gMhRyrRrhnKns

License: CC BY-NC-SA 4.0 (noncommercial)

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
COLON MAP: Colon Molecular Atlas Project→
41 datasets · comparison

Metadata

Technology
Visium
Organism
human
Tissue
intestine
Condition
colon adenocarcinoma
Modality
RNA
Observations (spots)
4,818
Tier
silver
Chemistry
Visium v1
Magnification
40x
Resolution
33,578 × 40,228 px
mpp
0.276 µm/px
Size
4.2 GB
Sample ID
MISC47
License
CC BY-NC-SA 4.0 NonCommercial
Published
Dec 7, 2023

Cite this dataset

doi.org/10.1016/j.cell.2023.11.006 ↗
BibTeX
@article{Heiser_2023,
  title = {Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors},
  volume = {186},
  ISSN = {0092-8674},
  url = {http://dx.doi.org/10.1016/j.cell.2023.11.006},
  DOI = {10.1016/j.cell.2023.11.006},
  number = {25},
  journal = {Cell},
  publisher = {Elsevier BV},
  author = {Heiser, Cody N. and Simmons, Alan J. and Revetta, Frank and McKinley, Eliot T. and Ramirez-Solano, Marisol A. and Wang, Jiawei and Kaur, Harsimran and Shao, Justin and Ayers, Gregory D. and Wang, Yu and Glass, Sarah E. and Tasneem, Naila and Chen, Zhengyi and Qin, Yan and Kim, William and Rolong, Andrea and Chen, Bob and Vega, Paige N. and Drewes, Julia L. and Markham, Nicholas O. and Saleh, Nabil and Nikolos, Fotis and Vandekar, Simon and Jones, Angela L. and Washington, M. Kay and Roland, Joseph T. and Chan, Keith S. and Schürpf, Thomas and Sears, Cynthia L. and Liu, Qi and Shrubsole, Martha J. and Coffey, Robert J. and Lau, Ken S.},
  year = {2023},
  month = Dec,
  pages = {5620–5637.e16}
}

Source: cell.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB