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Visium

Human infrapatellar fat pad

GSM8016283

silver Interactive viewer H&E osteoarthritis, knee ✓ Verified publication
Human infrapatellar fat pad preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8016283_KneeOA_ObeseBMI14_full_image': DataTree[cyx] (3, 3000, 3000), (3, 1500, 1500), (3, 750, 750), (3, 375, 375), (3, 187, 187)
│     ├── 'GSM8016283_KneeOA_ObeseBMI14_hires_image': DataArray[cyx] (3, 2000, 1510)
│     └── 'GSM8016283_KneeOA_ObeseBMI14_lowres_image': DataArray[cyx] (3, 600, 453)
├── Shapes
│     └── 'GSM8016283_KneeOA_ObeseBMI14': GeoDataFrame shape: (3034, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (3034, 18085)
with coordinate systems:
    ▸ 'GSM8016283_KneeOA_ObeseBMI14', with elements:
        GSM8016283_KneeOA_ObeseBMI14_full_image (Images), GSM8016283_KneeOA_ObeseBMI14_hires_image (Images), GSM8016283_KneeOA_ObeseBMI14_lowres_image (Images), GSM8016283_KneeOA_ObeseBMI14 (Shapes)
    ▸ 'GSM8016283_KneeOA_ObeseBMI14_downscaled_hires', with elements:
        GSM8016283_KneeOA_ObeseBMI14_hires_image (Images), GSM8016283_KneeOA_ObeseBMI14 (Shapes)
    ▸ 'GSM8016283_KneeOA_ObeseBMI14_downscaled_lowres', with elements:
        GSM8016283_KneeOA_ObeseBMI14_lowres_image (Images), GSM8016283_KneeOA_ObeseBMI14 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("iFa4spQHpAQW5irr0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("iFa4spQHpAQW5irr")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download iFa4spQHpAQW5irr0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/iFa4spQHpAQW5irr

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid iFa4spQHpAQW5irr

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
infrapatellar fat pad
Condition
osteoarthritis, knee
Modality
RNA
Observations (spots)
3,034
Tier
silver
Chemistry
Visium CytAssist v2
Resolution
1,510 × 2,000 px
mpp
4.037 µm/px
Size
35.3 MB
Sample ID
GSM8016283
License
NCBI GEO policy
Published
Oct 7, 2024

Cite this dataset

doi.org/10.1136/ard-2024-225928 ↗
BibTeX
@article{Peters_2025,
  title = {Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritis},
  volume = {84},
  ISSN = {0003-4967},
  url = {http://dx.doi.org/10.1136/ard-2024-225928},
  DOI = {10.1136/ard-2024-225928},
  number = {2},
  journal = {Annals of the Rheumatic Diseases},
  publisher = {Elsevier BV},
  author = {Peters, Hayley and Potla, Pratibha and Rockel, Jason S. and Tockovska, Teodora and Pastrello, Chiara and Jurisica, Igor and Delos Santos, Keemo and Vohra, Shabana and Fine, Noah and Lively, Starlee and Perry, Kim and Looby, Nikita and Li, Sheng Han and Chandran, Vinod and Hueniken, Katrina and Kaur, Paramvir and Perruccio, Anthony V. and Mahomed, Nizar N. and Rampersaud, Raja and Syed, Khalid and Gracey, Eric and Krawetz, Roman and Buechler, Matthew B. and Gandhi, Rajiv and Kapoor, Mohit},
  year = {2025},
  month = Feb,
  pages = {351–367}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB