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Visium

Human entorhinal cortex

GSM9235036

bronze Interactive viewer H&E Provisional
Human entorhinal cortex preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9235036_V13B23-364_B1_hires_image': DataArray[cyx] (3, 2000, 1845)
│     └── 'GSM9235036_V13B23-364_B1_lowres_image': DataArray[cyx] (3, 600, 554)
├── Shapes
│     └── 'GSM9235036_V13B23-364_B1': GeoDataFrame shape: (4992, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4992, 36601)
with coordinate systems:
    ▸ 'GSM9235036_V13B23-364_B1', with elements:
        GSM9235036_V13B23-364_B1_hires_image (Images), GSM9235036_V13B23-364_B1_lowres_image (Images), GSM9235036_V13B23-364_B1 (Shapes)
    ▸ 'GSM9235036_V13B23-364_B1_downscaled_hires', with elements:
        GSM9235036_V13B23-364_B1_hires_image (Images), GSM9235036_V13B23-364_B1 (Shapes)
    ▸ 'GSM9235036_V13B23-364_B1_downscaled_lowres', with elements:
        GSM9235036_V13B23-364_B1_lowres_image (Images), GSM9235036_V13B23-364_B1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("8lhwWC8XfvG21RtH0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("8lhwWC8XfvG21RtH")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 8lhwWC8XfvG21RtH0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/8lhwWC8XfvG21RtH

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 8lhwWC8XfvG21RtH

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
entorhinal cortex
Modality
RNA
Observations (spots)
4,992
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,845 × 2,000 px
mpp
4.274 µm/px
Size
30.6 MB
Sample ID
GSM9235036
License
NCBI GEO policy
Published
Nov 14, 2025

Cite this dataset

doi.org/10.1101/2025.11.20.689483 ↗
BibTeX
@article{Huuki_Myers_2025,
  title = {<i>APOE</i>
                  E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex},
  url = {http://dx.doi.org/10.1101/2025.11.20.689483},
  DOI = {10.1101/2025.11.20.689483},
  publisher = {openRxiv},
  author = {Huuki-Myers, Louise A. and Divecha, Heena R. and Bach, Svitlana V. and Valentine, Madeline R. and Eagles, Nicholas J. and Mulvey, Bernard and Bharadwaj, Rahul A. and Zhang, Ruth and Evans, James R. and Grant-Peters, Melissa and Miller, Ryan A. and Kleinman, Joel E. and Han, Shizhong and Hyde, Thomas M. and Page, Stephanie C. and Weinberger, Daniel R. and Martinowich, Keri and Ryten, Mina and Maynard, Kristen R. and Collado-Torres, Leonardo},
  year = {2025},
  month = Nov
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB