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Visium

Human craniocervical region

GSM5494480

bronze Interactive viewer H&E head and neck squamous cell carcinoma Provisional
Human craniocervical region preview
print(sdata)
SpatialData object
├── Images
│     └── 'GSM5494480_P210325T3_hires_image': DataArray[cyx] (3, 2000, 1946)
├── Shapes
│     └── 'GSM5494480_P210325T3': GeoDataFrame shape: (1853, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1853, 36601)
with coordinate systems:
    ▸ 'GSM5494480_P210325T3', with elements:
        GSM5494480_P210325T3_hires_image (Images), GSM5494480_P210325T3 (Shapes)
    ▸ 'GSM5494480_P210325T3_downscaled_hires', with elements:
        GSM5494480_P210325T3_hires_image (Images), GSM5494480_P210325T3 (Shapes)
    ▸ 'GSM5494480_P210325T3_downscaled_lowres', with elements:
        GSM5494480_P210325T3 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("XMPlJQ3XNx5sBcXR0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("XMPlJQ3XNx5sBcXR")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download XMPlJQ3XNx5sBcXR0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/XMPlJQ3XNx5sBcXR

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid XMPlJQ3XNx5sBcXR

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
craniocervical region
Condition
head and neck squamous cell carcinoma
Modality
RNA
Observations (spots)
1,853
Tier
bronze
Chemistry
Visium v1
Resolution
1,946 × 2,000 px
mpp
3.881 µm/px
Size
14.4 MB
Sample ID
GSM5494480
License
NCBI GEO policy
Published
Aug 29, 2022

Cite this dataset

doi.org/10.1136/jitc-2022-004832 ↗
BibTeX
@article{Cheng_2022,
  title = {Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance},
  volume = {10},
  ISSN = {2051-1426},
  url = {http://dx.doi.org/10.1136/jitc-2022-004832},
  DOI = {10.1136/jitc-2022-004832},
  number = {8},
  journal = {Journal for ImmunoTherapy of Cancer},
  publisher = {BMJ},
  author = {Cheng, Han-Ying and Hsieh, Chia-Hsin and Lin, Po-Han and Chen, Yu-Tung and Hsu, Dennis Shin-Shian and Tai, Shyh-Kuan and Chu, Pen-Yuan and Yang, Muh-Hwa},
  year = {2022},
  month = Aug,
  pages = {e004832}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB