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Visium

Human craniocervical region

GSM5494475

bronze Interactive viewer H&E head and neck squamous cell carcinoma Provisional
Human craniocervical region preview
print(sdata)
SpatialData object
├── Images
│     └── 'GSM5494475_HNSCC201125T04_hires_image': DataArray[cyx] (3, 1972, 2000)
├── Shapes
│     └── 'GSM5494475_HNSCC201125T04': GeoDataFrame shape: (1155, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1155, 36601)
with coordinate systems:
    ▸ 'GSM5494475_HNSCC201125T04', with elements:
        GSM5494475_HNSCC201125T04_hires_image (Images), GSM5494475_HNSCC201125T04 (Shapes)
    ▸ 'GSM5494475_HNSCC201125T04_downscaled_hires', with elements:
        GSM5494475_HNSCC201125T04_hires_image (Images), GSM5494475_HNSCC201125T04 (Shapes)
    ▸ 'GSM5494475_HNSCC201125T04_downscaled_lowres', with elements:
        GSM5494475_HNSCC201125T04 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("rJDSTlQPlnM8l2X00000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("rJDSTlQPlnM8l2X0")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download rJDSTlQPlnM8l2X00000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/rJDSTlQPlnM8l2X0

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid rJDSTlQPlnM8l2X0

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
craniocervical region
Condition
head and neck squamous cell carcinoma
Modality
RNA
Observations (spots)
1,155
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 1,972 px
mpp
3.415 µm/px
Size
14.0 MB
Sample ID
GSM5494475
License
NCBI GEO policy
Published
Aug 29, 2022

Cite this dataset

doi.org/10.1136/jitc-2022-004832 ↗
BibTeX
@article{Cheng_2022,
  title = {Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance},
  volume = {10},
  ISSN = {2051-1426},
  url = {http://dx.doi.org/10.1136/jitc-2022-004832},
  DOI = {10.1136/jitc-2022-004832},
  number = {8},
  journal = {Journal for ImmunoTherapy of Cancer},
  publisher = {BMJ},
  author = {Cheng, Han-Ying and Hsieh, Chia-Hsin and Lin, Po-Han and Chen, Yu-Tung and Hsu, Dennis Shin-Shian and Tai, Shyh-Kuan and Chu, Pen-Yuan and Yang, Muh-Hwa},
  year = {2022},
  month = Aug,
  pages = {e004832}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB