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Visium

Mouse colon

GSM8694494

bronze Interactive viewer H&E colorectal cancer Provisional
Mouse colon preview
print(sdata)
SpatialData object
├── Images
│     └── 'GSM8694494_MC38_IgG_m04_sec1_hires_image': DataArray[cyx] (3, 2000, 2000)
├── Shapes
│     └── 'GSM8694494_MC38_IgG_m04_sec1': GeoDataFrame shape: (2465, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2465, 20551)
with coordinate systems:
    ▸ 'GSM8694494_MC38_IgG_m04_sec1', with elements:
        GSM8694494_MC38_IgG_m04_sec1_hires_image (Images), GSM8694494_MC38_IgG_m04_sec1 (Shapes)
    ▸ 'GSM8694494_MC38_IgG_m04_sec1_downscaled_hires', with elements:
        GSM8694494_MC38_IgG_m04_sec1_hires_image (Images), GSM8694494_MC38_IgG_m04_sec1 (Shapes)
    ▸ 'GSM8694494_MC38_IgG_m04_sec1_downscaled_lowres', with elements:
        GSM8694494_MC38_IgG_m04_sec1 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("oG4Uxrif21b3uVjn0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("oG4Uxrif21b3uVjn")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download oG4Uxrif21b3uVjn0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/oG4Uxrif21b3uVjn

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid oG4Uxrif21b3uVjn

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
mouse
Tissue
colon
Condition
colorectal cancer
Modality
RNA
Observations (spots)
2,465
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
2,000 × 2,000 px
mpp
3.330 µm/px
Size
26.6 MB
Sample ID
GSM8694494
License
NCBI GEO policy
Published
Mar 10, 2025

Cite this dataset

doi.org/10.3389/fonc.2025.1549237 ↗
BibTeX
@article{Kavran_2025,
  title = {Spatial genomics reveals cholesterol metabolism as a key factor in colorectal cancer immunotherapy resistance},
  volume = {15},
  ISSN = {2234-943X},
  url = {http://dx.doi.org/10.3389/fonc.2025.1549237},
  DOI = {10.3389/fonc.2025.1549237},
  journal = {Frontiers in Oncology},
  publisher = {Frontiers Media SA},
  author = {Kavran, Andrew J. and Bai, Yulong and Rabe, Brian and Kreshock, Anna and Fisher, Andrew and Cheng, Yelena and Lewin, Anne and Dai, Chao and Meyer, Matthew J. and Mavrakis, Konstantinos J. and Lyubetskaya, Anna and Drokhlyansky, Eugene},
  year = {2025},
  month = Mar
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB