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Visium

Mouse brain

GSM8035260

bronze Interactive viewer H&E Provisional
Mouse brain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8035260_C1_21dpi_hires_image': DataArray[cyx] (3, 2000, 1932)
│     └── 'GSM8035260_C1_21dpi_lowres_image': DataArray[cyx] (3, 600, 580)
├── Shapes
│     └── 'GSM8035260_C1_21dpi': GeoDataFrame shape: (2170, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2170, 32285)
with coordinate systems:
    ▸ 'GSM8035260_C1_21dpi', with elements:
        GSM8035260_C1_21dpi_hires_image (Images), GSM8035260_C1_21dpi_lowres_image (Images), GSM8035260_C1_21dpi (Shapes)
    ▸ 'GSM8035260_C1_21dpi_downscaled_hires', with elements:
        GSM8035260_C1_21dpi_hires_image (Images), GSM8035260_C1_21dpi (Shapes)
    ▸ 'GSM8035260_C1_21dpi_downscaled_lowres', with elements:
        GSM8035260_C1_21dpi_lowres_image (Images), GSM8035260_C1_21dpi (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("Iz94jEypzRkSo0gD0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Iz94jEypzRkSo0gD")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download Iz94jEypzRkSo0gD0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Iz94jEypzRkSo0gD

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Iz94jEypzRkSo0gD

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
mouse
Tissue
brain
Modality
RNA
Observations (spots)
2,170
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,932 × 2,000 px
mpp
3.671 µm/px
Size
39.2 MB
Sample ID
GSM8035260
License
NCBI GEO policy
Published
Jun 30, 2025

Cite this dataset

doi.org/10.1038/s41586-025-09449-2 ↗
BibTeX
@article{Ewing_Crystal_2025,
  title = {Dynamic fibroblast–immune interactions shape recovery after brain injury},
  volume = {646},
  ISSN = {1476-4687},
  url = {http://dx.doi.org/10.1038/s41586-025-09449-2},
  DOI = {10.1038/s41586-025-09449-2},
  number = {8086},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  author = {Ewing-Crystal, Nathan A. and Mroz, Nicholas M. and Larpthaveesarp, Amara and Lizama, Carlos O. and Pennington, Remy and Chiaranunt, Pailin and Dennis, Jason I. and Chang, Anthony A. and Merrill, Eric Dean and Caryotakis, Sofia E. and Kirthivasan, Nikhita and Teo, Leon and Tsukui, Tatsuya and Katewa, Aditya and McKinsey, Gabriel L. and Nelson, Sophia C. K. and Ciesielska, Agnieszka and Lummis, Nicole C. and Pintarić, Lucija and Dahlgren, Madelene W. and Atakilit, Amha and Paidassi, Helena and Jain, Saket and Liu, Xiaodan and Xu, Duan and Aghi, Manish K. and Bourne, James A. and Paz, Jeanne T. and Daneman, Richard and Gonzalez, Fernando F. and Sheppard, Dean and Molofsky, Anna V. and Arnold, Thomas D. and Molofsky, Ari B.},
  year = {2025},
  month = Sept,
  pages = {934–944}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB