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Visium

Human brain

GSM7759705

bronze Interactive viewer H&E brain glioma Provisional
Human brain preview
print(sdata)
SpatialData object
├── Images
│     └── 'GSM7759705_Oligodendroglioma8_hires_image': DataArray[cyx] (3, 1944, 2000)
├── Shapes
│     └── 'GSM7759705_Oligodendroglioma8': GeoDataFrame shape: (3567, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (3567, 36601)
with coordinate systems:
    ▸ 'GSM7759705_Oligodendroglioma8', with elements:
        GSM7759705_Oligodendroglioma8_hires_image (Images), GSM7759705_Oligodendroglioma8 (Shapes)
    ▸ 'GSM7759705_Oligodendroglioma8_downscaled_hires', with elements:
        GSM7759705_Oligodendroglioma8_hires_image (Images), GSM7759705_Oligodendroglioma8 (Shapes)
    ▸ 'GSM7759705_Oligodendroglioma8_downscaled_lowres', with elements:
        GSM7759705_Oligodendroglioma8 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("iuO0aTjrVSSWy7cB0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("iuO0aTjrVSSWy7cB")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download iuO0aTjrVSSWy7cB0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/iuO0aTjrVSSWy7cB

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid iuO0aTjrVSSWy7cB

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
human
Tissue
brain
Condition
brain glioma
Modality
RNA
Observations (spots)
3,567
Tier
bronze
Chemistry
Visium v1
Resolution
2,000 × 1,944 px
mpp
3.416 µm/px
Size
26.5 MB
Sample ID
GSM7759705
License
NCBI GEO policy
Published
Jan 2, 2025

Cite this dataset

doi.org/10.1038/s41467-025-59805-z ↗
BibTeX
@article{Webb_2025,
  title = {Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas},
  volume = {16},
  ISSN = {2041-1723},
  url = {http://dx.doi.org/10.1038/s41467-025-59805-z},
  DOI = {10.1038/s41467-025-59805-z},
  number = {1},
  journal = {Nature Communications},
  publisher = {Springer Science and Business Media LLC},
  author = {Webb, Michelle G. and Chow, Frances and McCullough, Carmel G. and Zhang, Bohan and Lee, John J. Y. and Bassiouni, Rania and Garrett, Norman E. and Hurth, Kyle and Carpten, John D. and Zada, Gabriel and Craig, David W.},
  year = {2025},
  month = June
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB