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Visium

Mouse brain

GSM5519055

bronze Interactive viewer H&E Provisional
Mouse brain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM5519055_hemeHpx_1000_hires_image': DataArray[cyx] (3, 2000, 1771)
│     └── 'GSM5519055_hemeHpx_1000_lowres_image': DataArray[cyx] (3, 600, 531)
├── Shapes
│     └── 'GSM5519055_hemeHpx_1000': GeoDataFrame shape: (2936, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2936, 26124)
with coordinate systems:
    ▸ 'GSM5519055_hemeHpx_1000', with elements:
        GSM5519055_hemeHpx_1000_hires_image (Images), GSM5519055_hemeHpx_1000_lowres_image (Images), GSM5519055_hemeHpx_1000 (Shapes)
    ▸ 'GSM5519055_hemeHpx_1000_downscaled_hires', with elements:
        GSM5519055_hemeHpx_1000_hires_image (Images), GSM5519055_hemeHpx_1000 (Shapes)
    ▸ 'GSM5519055_hemeHpx_1000_downscaled_lowres', with elements:
        GSM5519055_hemeHpx_1000_lowres_image (Images), GSM5519055_hemeHpx_1000 (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("4N1mcnugE77SMwNo0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("4N1mcnugE77SMwNo")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 4N1mcnugE77SMwNo0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/4N1mcnugE77SMwNo

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 4N1mcnugE77SMwNo

License: NCBI GEO policy

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Metadata

Technology
Visium
Organism
mouse
Tissue
brain
Modality
RNA
Observations (spots)
2,936
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,771 × 2,000 px
mpp
4.219 µm/px
Size
43.8 MB
Sample ID
GSM5519055
License
NCBI GEO policy
Published
Nov 25, 2021

Cite this dataset

doi.org/10.1016/j.freeradbiomed.2021.11.011 ↗
BibTeX
@article{Buzzi_2022,
  title = {Spatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain},
  volume = {179},
  ISSN = {0891-5849},
  url = {http://dx.doi.org/10.1016/j.freeradbiomed.2021.11.011},
  DOI = {10.1016/j.freeradbiomed.2021.11.011},
  journal = {Free Radical Biology and Medicine},
  publisher = {Elsevier BV},
  author = {Buzzi, Raphael M. and Akeret, Kevin and Schwendinger, Nina and Klohs, Jan and Vallelian, Florence and Hugelshofer, Michael and Schaer, Dominik J.},
  year = {2022},
  month = Feb,
  pages = {277–287}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB