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Visium HD

Human kidney

GSM9467249

bronze Interactive viewer H&E type 2 diabetes mellitus Provisional
Human kidney preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9467249_patient1_hires_image': DataArray[cyx] (3, 6000, 5266)
│     └── 'GSM9467249_patient1_lowres_image': DataArray[cyx] (3, 600, 527)
├── Shapes
│     ├── 'GSM9467249_patient1_square_008um': GeoDataFrame shape: (154937, 1) (2D shapes)
│     └── 'GSM9467249_patient1_square_008um_for_vitessce': GeoDataFrame shape: (154937, 2) (2D shapes)
└── Tables
      └── 'square_008um': AnnData (154937, 37082)
with coordinate systems:
    ▸ 'GSM9467249_patient1', with elements:
        GSM9467249_patient1_hires_image (Images), GSM9467249_patient1_lowres_image (Images), GSM9467249_patient1_square_008um (Shapes), GSM9467249_patient1_square_008um_for_vitessce (Shapes)
    ▸ 'GSM9467249_patient1_downscaled_hires', with elements:
        GSM9467249_patient1_hires_image (Images), GSM9467249_patient1_square_008um (Shapes), GSM9467249_patient1_square_008um_for_vitessce (Shapes)
    ▸ 'GSM9467249_patient1_downscaled_lowres', with elements:
        GSM9467249_patient1_lowres_image (Images), GSM9467249_patient1_square_008um (Shapes), GSM9467249_patient1_square_008um_for_vitessce (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("bv10bJQZ5klI5nMu0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("bv10bJQZ5klI5nMu")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download bv10bJQZ5klI5nMu0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/bv10bJQZ5klI5nMu

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid bv10bJQZ5klI5nMu

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium HD
Organism
human
Tissue
kidney
Condition
type 2 diabetes mellitus
Modality
RNA
Observations (bins)
154,937
Tier
bronze
Magnification
20x
Resolution
5,266 × 6,000 px
mpp
0.549 µm/px
Size
67.2 MB
Sample ID
GSM9467249
License
NCBI GEO policy
Published
Feb 5, 2026

Cite this dataset

doi.org/10.1038/s41392-026-02653-0 ↗
BibTeX
@article{Nair_2026,
  title = {Hypoxia inducible factor network reflects kidney disease progression in diabetes and sodium-glucose co-transporters inhibition},
  volume = {11},
  ISSN = {2059-3635},
  url = {http://dx.doi.org/10.1038/s41392-026-02653-0},
  DOI = {10.1038/s41392-026-02653-0},
  number = {1},
  journal = {Signal Transduction and Targeted Therapy},
  publisher = {Springer Science and Business Media LLC},
  author = {Nair, Viji and Minakawa, Akihiro and Smith, Cathy and Berthier, Celine C. and Hartman, John and Menon, Rajasree and Fermin, Damian and Otto, Edgar A. and Gisch, Debora L. and Eadon, Michael T. and Jain, Sanjay and Choi, Ye Ji and Pyle, Laura and Eichinger, Felix and Alakwaa, Fadhl M. and Rose, Michael P. and Subramanian, Lalita and El Saghir, Jamal and Beamish, Jeffrey A. and Hodgin, Jeffrey B. and Brosius, Frank C. and Bjornstad, Petter and Nelson, Peter J. and Harder, Jennifer L. and Werner, Thomas and Kretzler, Matthias and Schaub, Jennifer A.},
  year = {2026},
  month = Apr
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB