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Visium HD

Human bone element

GSM9556003

silver Interactive viewer H&E Ewing sarcoma No linked publication
Human bone element preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM9556003_033_pre_hires_image': DataArray[cyx] (3, 6000, 4580)
│     └── 'GSM9556003_033_pre_lowres_image': DataArray[cyx] (3, 600, 458)
├── Shapes
│     ├── 'GSM9556003_033_pre_square_008um': GeoDataFrame shape: (10355, 1) (2D shapes)
│     └── 'GSM9556003_033_pre_square_008um_for_vitessce': GeoDataFrame shape: (10355, 2) (2D shapes)
└── Tables
      └── 'square_008um': AnnData (10355, 18085)
with coordinate systems:
    ▸ 'GSM9556003_033_pre', with elements:
        GSM9556003_033_pre_hires_image (Images), GSM9556003_033_pre_lowres_image (Images), GSM9556003_033_pre_square_008um (Shapes), GSM9556003_033_pre_square_008um_for_vitessce (Shapes)
    ▸ 'GSM9556003_033_pre_downscaled_hires', with elements:
        GSM9556003_033_pre_hires_image (Images), GSM9556003_033_pre_square_008um (Shapes), GSM9556003_033_pre_square_008um_for_vitessce (Shapes)
    ▸ 'GSM9556003_033_pre_downscaled_lowres', with elements:
        GSM9556003_033_pre_lowres_image (Images), GSM9556003_033_pre_square_008um (Shapes), GSM9556003_033_pre_square_008um_for_vitessce (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("DBbUxBEFDEdR96lE0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("DBbUxBEFDEdR96lE")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download DBbUxBEFDEdR96lE0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/DBbUxBEFDEdR96lE

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid DBbUxBEFDEdR96lE

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
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Metadata

Technology
Visium HD
Organism
human
Tissue
bone element
Condition
Ewing sarcoma
Modality
RNA
Observations (bins)
10,355
Tier
silver
Resolution
4,580 × 6,000 px
mpp
1.437 µm/px
Size
25.4 MB
Sample ID
GSM9556003
License
NCBI GEO policy
Published
Mar 2, 2026

Cite this dataset

doi.org/10.1038/s41591-026-04340-7 ↗
BibTeX
@article{geo:GSE322640,
  title = {Trabectedin and low-dose irinotecan to target EWS::FLI1 in Ewing sarcoma: a phase 1/2 trial},
  volume = {32},
  ISSN = {1546-170X},
  url = {http://dx.doi.org/10.1038/s41591-026-04340-7},
  DOI = {10.1038/s41591-026-04340-7},
  number = {6},
  journal = {Nature Medicine},
  publisher = {Springer Science and Business Media LLC},
  author = {Grohar, Patrick J. and Heise, Rachel and Wedekind, Mary Frances and Ballman, Karla and Mascarenhas, Leo and DuBois, Steven G. and Maki, Robert G. and Boguslawski, Elissa A. and Gedminas, Jenna M. and Wilson, Elizabeth R. and Thomas, Elaine and Segers, Blair and Surrey, Lea F. and Ricker, Cora and Klega, Kelly and Navid, Fariba and Lam, Gretchen Y. and The, Stephanie and Kaufman, Rebecca and Roberts, Ryan D. and Hayashi, Masanori and Mena, Esther and Overman, Lindsey and Peer, Cody and Schmidt, Keith and Diamond, Mark S. and Figg, William D. and Bagatell, Rochelle and Liza Lindenberg, M. and Choyke, Peter L. and Crompton, Brian D. and Widemann, Brigitte C. and Glod, John W. and Laetsch, Theodore W. and Reinke, Denise K. and Chugh, Rashmi},
  year = {2026},
  month = Apr,
  pages = {2227–2237}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB