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spatial transcriptomics

Human heart

SPA35

silver Interactive viewer H&E ✓ Verified publication
Human heart preview
print(sdata)
SpatialData object
├── Images
│     └── 'SPA35_full_image': DataTree[cyx] (3, 8602, 9830), (3, 4301, 4915), (3, 2150, 2457), (3, 1075, 1228)
├── Shapes
│     └── 'SPA35_spots': GeoDataFrame shape: (238, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (238, 39739)
with coordinate systems:
    ▸ 'global', with elements:
        SPA35_full_image (Images), SPA35_spots (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("5YaKaF4fzPr9rrdp0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("5YaKaF4fzPr9rrdp")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 5YaKaF4fzPr9rrdp0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/5YaKaF4fzPr9rrdp

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 5YaKaF4fzPr9rrdp

License: CC BY-NC-SA 4.0 (noncommercial)

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Metadata

Technology
spatial transcriptomics
Organism
human
Tissue
heart
Modality
RNA
Observations (spots)
238
Tier
silver
Chemistry
ST 1k
Resolution
9,830 × 8,602 px
mpp
0.908 µm/px
Size
136 MB
Sample ID
SPA35
License
CC BY-NC-SA 4.0 NonCommercial
Published
Dec 16, 2019

Cite this dataset

doi.org/10.1016/j.cell.2019.11.025 ↗
BibTeX
@article{Asp_2019,
  title = {A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart},
  volume = {179},
  ISSN = {0092-8674},
  url = {http://dx.doi.org/10.1016/j.cell.2019.11.025},
  DOI = {10.1016/j.cell.2019.11.025},
  number = {7},
  journal = {Cell},
  publisher = {Elsevier BV},
  author = {Asp, Michaela and Giacomello, Stefania and Larsson, Ludvig and Wu, Chenglin and Fürth, Daniel and Qian, Xiaoyan and Wärdell, Eva and Custodio, Joaquin and Reimegård, Johan and Salmén, Fredrik and Österholm, Cecilia and Ståhl, Patrik L. and Sundström, Erik and Åkesson, Elisabet and Bergmann, Olaf and Bienko, Magda and Månsson-Broberg, Agneta and Nilsson, Mats and Sylvén, Christer and Lundeberg, Joakim},
  year = {2019},
  month = Dec,
  pages = {1647–1660.e19}
}

Source: sciencedirect.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB