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MIBIscope (MIBI-TOF)

Human breast

Risom et al., Cell 2022, "Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma" (pt1058)

bronze invasive ductal breast carcinoma Provisional
MIBIscope (MIBI-TOF)
print(sdata)
SpatialData object
├── Images
│     └── 'Point4136_pt1058_31850_image': DataTree[cyx] (46, 1024, 1024), (46, 512, 512), (46, 256, 256), (46, 128, 128), (46, 64, 64)
├── Labels
│     └── 'Point4136_pt1058_31850_whole_cell_labels': DataTree[yx] (1024, 1024), (512, 512), (256, 256), (128, 128), (64, 64)
├── Shapes
│     └── 'Point4136_pt1058_31850_cell_boundaries': GeoDataFrame shape: (1016, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1016, 46)
with coordinate systems:
    ▸ 'global', with elements:
        Point4136_pt1058_31850_image (Images), Point4136_pt1058_31850_whole_cell_labels (Labels), Point4136_pt1058_31850_cell_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("64VbGKTpbg1n6ncF0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("64VbGKTpbg1n6ncF")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download 64VbGKTpbg1n6ncF0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/64VbGKTpbg1n6ncF

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid 64VbGKTpbg1n6ncF

License: CC BY 4.0

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78 datasets · publication

Metadata

Technology
MIBIscope (MIBI-TOF)
Vendor
Ionpath
Organism
human
Tissue
breast
Condition
invasive ductal breast carcinoma
Modality
protein
Observations (cells)
1,016
Tier
bronze
Chemistry
MIBI
Staining
Antibodies
Size
5.9 MB
Sample ID
d87vg86zd8:pt1058
License
CC BY 4.0
Published
Mar 17, 2022

Cite this dataset

doi.org/10.17632/d87vg86zd8.3 ↗
BibTeX
@article{mendeley:d87vg86zd8,
  doi = {10.17632/d87vg86zd8.3},
  title = {Risom et al., Cell 2022, "Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma" (pt1047)}
}

Source: data.mendeley.com ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB