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10x Xenium

Human sigmoid colon

GSM9736143

bronze Interactive viewer ulcerative colitis Provisional
Human sigmoid colon preview
print(sdata)
SpatialData object
├── Images
│     └── 'morphology_mip': DataTree[cyx] (1, 27268, 14119), (1, 13634, 7059), (1, 6817, 3529), (1, 3408, 1764), (1, 1704, 882)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (22693, 13512), (11346, 6756), (5673, 3378), (2836, 1689), (1418, 844)
│     └── 'nucleus_labels': DataTree[yx] (23711, 13537), (11855, 6768), (5927, 3384), (2963, 1692), (1481, 846)
├── Points
│     └── 'transcripts': DataFrame with shape: (10131117, 13) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (33939, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (33939, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (34335, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (33939, 480)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("Ec9cf332doO3xLOs0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Ec9cf332doO3xLOs")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download Ec9cf332doO3xLOs0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Ec9cf332doO3xLOs

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Ec9cf332doO3xLOs

License: NCBI GEO policy

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Metadata

Technology
10x Xenium
Organism
human
Tissue
sigmoid colon
Condition
ulcerative colitis
Modality
RNA
Observations (cells)
33,939
Transcripts
10,131,117
Tier
bronze
Size
449 MB
Sample ID
GSM9736143
License
NCBI GEO policy
Published
Sep 3, 2026

Cite this dataset

doi.org/10.1126/science.aeh7112 ↗
BibTeX
@article{geo:GSM9736143,
  doi = {10.1126/science.aeh7112},
  title = {GSM9736143},
  year = {2026}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB