← All datasets
Xenium

Human liver

A Single-Cell Atlas Of Human Pediatric Liver Reveals Age-Related Hepatic Gene Signatures: C95 (Liver – Caudate)

bronze Interactive viewer Provisional
Xenium
print(sdata)
SpatialData object
├── Images
│     ├── 'morphology_focus': DataTree[cyx] (1, 23911, 48299), (1, 11955, 24149), (1, 5977, 12074), (1, 2988, 6037), (1, 1494, 3018)
│     └── 'morphology_mip': DataTree[cyx] (1, 23911, 48299), (1, 11955, 24149), (1, 5977, 12074), (1, 2988, 6037), (1, 1494, 3018)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (23911, 48299), (11955, 24149), (5977, 12074), (2988, 6037), (1494, 3018)
│     └── 'nucleus_labels': DataTree[yx] (23911, 48299), (11955, 24149), (5977, 12074), (2988, 6037), (1494, 3018)
├── Points
│     └── 'transcripts': DataFrame with shape: (62284243, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (142659, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (142659, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (142659, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (142659, 477)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("kAMpfNxWkvyw5Pcp0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("kAMpfNxWkvyw5Pcp")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download kAMpfNxWkvyw5Pcp0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/kAMpfNxWkvyw5Pcp

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid kAMpfNxWkvyw5Pcp

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
geo-gse286254→
7 datasets · publication

Metadata

Technology
Xenium
Vendor
10x Genomics
Organism
human
Tissue
liver
Modality
RNA
Observations (cells)
142,659
Transcripts
62,284,243
Target genes
477
Tier
bronze
Size
5.2 GB
Sample ID
GSM8721782
License
NCBI GEO policy
Published
Jul 18, 2025

Cite this dataset

doi.org/10.1101/2025.04.16.649149 ↗
BibTeX
@article{geo:GSE286254,
  doi = {10.1101/2025.04.16.649149},
  title = {A Single-Cell Atlas Of Human Pediatric Liver Reveals Age-Related Hepatic Gene Signatures: C101 (Liver – Caudate)},
  year = {2025}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB