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10x Xenium

Human brain

ffpe-human-brain-cancer-data-with-human-immuno-oncology-profiling-panel-and-custom-add-on-1-standard

silver Interactive viewer H&E glioblastoma multiforme No linked publication
Human brain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'he_image': DataTree[cyx] (3, 58584, 38957), (3, 29292, 19478), (3, 14646, 9739), (3, 7323, 4869), (3, 3661, 2434)
│     └── 'morphology_focus': DataTree[cyx] (4, 51043, 53946), (4, 25521, 26973), (4, 12760, 13486), (4, 6380, 6743), (4, 3190, 3371)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (51043, 53946), (25521, 26973), (12760, 13486), (6380, 6743), (3190, 3371)
│     └── 'nucleus_labels': DataTree[yx] (51043, 53946), (25521, 26973), (12760, 13486), (6380, 6743), (3190, 3371)
├── Points
│     └── 'transcripts': DataFrame with shape: (178716169, 11) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (816769, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (816769, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (818128, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (816769, 480)
with coordinate systems:
    ▸ 'global', with elements:
        he_image (Images), morphology_focus (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("iHSXYBFbeAMN3zxa0001")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("iHSXYBFbeAMN3zxa")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download iHSXYBFbeAMN3zxa0001 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/iHSXYBFbeAMN3zxa

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid iHSXYBFbeAMN3zxa

License: CC BY 4.0

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
10x Xenium
Organism
human
Tissue
brain
Condition
glioblastoma multiforme
Modality
RNA
Observations (cells)
816,769
Transcripts
178,716,169
Tier
silver
Chemistry
Xenium v1
Resolution
38,957 × 58,584 px
Size
30.1 GB
Sample ID
ffpe-human-brain-cancer-data-with-human-immuno-oncology-profiling-panel-and-custom-add-on-1-standard
License
CC BY 4.0
Published
Apr 15, 2024

Cite this dataset

No linked publication found — please cite the data source: 10x Genomics ↗.

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB