← All datasets
10x Xenium

Human ascending aorta

GSM9194125

bronze Interactive viewer IgG4-related disease Provisional
Human ascending aorta preview
print(sdata)
SpatialData object
├── Images
│     └── 'morphology_mip': DataTree[cyx] (1, 31283, 48305), (1, 15641, 24152), (1, 7820, 12076), (1, 3910, 6038), (1, 1955, 3019)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (28195, 46103), (14097, 23051), (7048, 11525), (3524, 5762), (1762, 2881)
│     └── 'nucleus_labels': DataTree[yx] (28150, 46058), (14075, 23029), (7037, 11514), (3518, 5757), (1759, 2878)
├── Points
│     └── 'transcripts': DataFrame with shape: (5051417, 11) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (59298, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (59298, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (59298, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (59298, 377)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Python · sddb client
from sddb import Catalog

ds = Catalog().dataset("ROrfUT8gQOmJlx2r0000")
ds.elements()          # inspect without downloading
sdata = ds.to_sdata()  # cached locally, reused
print(sdata)
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("ROrfUT8gQOmJlx2r")   # stem uid: Lamin resolves it to the latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Shell
# sddb client: download the .zarr into data/
sddb-cli download ROrfUT8gQOmJlx2r0000 --dest data/

# or lamin: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/ROrfUT8gQOmJlx2r

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid ROrfUT8gQOmJlx2r

License: NCBI GEO policy

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
Spatial gene expression profiling of aortitis samples.→
10 datasets · comparison

Metadata

Technology
10x Xenium
Organism
human
Tissue
ascending aorta
Condition
IgG4-related disease
Modality
RNA
Observations (cells)
59,298
Transcripts
5,051,417
Tier
bronze
Size
1.5 GB
Sample ID
GSM9194125
License
NCBI GEO policy
Published
Feb 5, 2026

Cite this dataset

doi.org/10.1172/jci.insight.200255 ↗
BibTeX
@article{geo:GSM9194125,
  doi = {10.1172/jci.insight.200255},
  title = {GSM9194125},
  year = {2026}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB