Collections / Interleukin-34 induced Arg1+ macrophages play a key role in breast cancer brain metastasis

Interleukin-34 induced Arg1+ macrophages play a key role in breast cancer brain metastasis

We use 10x Genomics to perform the visium RNA sequencing on two tumor tissue, which showed cell type clusters and whole genome profiling in each cell clusters. Visium CytAssist Spatial Gene Expression kit was used for FFPE (Mouse Transcriptome, 6.5 mm, 4 rxns, PN-1000521,10x Genomics).

Datasets2
Size~155 MB
AssayVisium
Samplemouse · brain
KindOther
Flag a data issue
PMID:42166785 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse325996")
cohort.members        # the 2 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse325996")
coll.ordered_artifacts.to_dataframe()   # the 2 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse325996 --dest data/

Licenses: 2 NCBI GEO policy

Open in Vitessce
Visium
Mouse brain
GSM9618494
mouse brain breast cancer 70.5 MB 3,406 spots bronze H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuebrain
Conditionbreast cancer
Size70.5 MB
Spots3,406
bronze H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse brain
GSM9618495
mouse brain breast cancer 84.0 MB 4,017 spots bronze H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuebrain
Conditionbreast cancer
Size84.0 MB
Spots4,017
bronze H&E NCBI GEO policy Open in Vitessce

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No linked publication found — please cite the data source.