Collections / Spatial transcriptomics of MRGPRX4-driven melanoma

Spatial transcriptomics of MRGPRX4-driven melanoma

Spatial transcriptomics was performed on skin samples from TyrCreER;MRGPRX4-ROSA26-stop-flox animals. Spatial analysis revealed mutiple, spatially defined melanoma states.

Datasets3
Size~36.4 MB
AssayVisium
Samplemouse · skin of body
KindOther
Flag a data issue
www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE313828 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse313828")
cohort.members        # the 3 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse313828")
coll.ordered_artifacts.to_dataframe()   # the 3 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse313828 --dest data/

Licenses: 3 NCBI GEO policy

Visium
Mouse skin of body
GSM9376204
mouse skin of body melanoma 12.2 MB 462 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueskin of body
Conditionmelanoma
Size12.2 MB
Spots462
silver H&E NCBI GEO policy
Open in Vitessce
Visium
Mouse skin of body
GSM9376205
mouse skin of body melanoma 12.2 MB 498 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueskin of body
Conditionmelanoma
Size12.2 MB
Spots498
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse skin of body
GSM9376206
mouse skin of body melanoma 12.0 MB 386 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueskin of body
Conditionmelanoma
Size12.0 MB
Spots386
silver H&E NCBI GEO policy Open in Vitessce

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