Collections / Targeting circulating mechanoresponsive monocytes and macrophages to reduce fibrosis

Targeting circulating mechanoresponsive monocytes and macrophages to reduce fibrosis

We performed single-cell RNA sequencing on skin, wounded tissue, or wounded tissue subjected to mechanical strain. Wounds could be treated with focal adhesion kinase inhibitor (FAKI) hydrogels or in mice with FAK knocked out in the myeloid cells.

Datasets2
Size~20.6 MB
AssayVisium
Samplehuman · skin of body
KindOther
Flag a data issue
PMID:41120571 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse297064")
cohort.members        # the 2 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse297064")
coll.ordered_artifacts.to_dataframe()   # the 2 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse297064 --dest data/

Licenses: 2 NCBI GEO policy

Visium
Human skin of body
GSM8983043
human skin of body 12.6 MB 2,581 spots bronze H&E NCBI GEO policy
TechnologyVisium
Organismhuman
Tissueskin of body
Size12.6 MB
Spots2,581
bronze H&E NCBI GEO policy
Open in Vitessce
Visium
Human skin of body
GSM8983044
human skin of body 8.0 MB 943 spots bronze H&E NCBI GEO policy
TechnologyVisium
Organismhuman
Tissueskin of body
Size8.0 MB
Spots943
bronze H&E NCBI GEO policy Open in Vitessce

Cite this collection

No linked publication found — please cite the data source.